SCLC Flashcards
1
Q
Morphology of SCLC on pathology
A
small round blue cell tumor
2
Q
SCLC stains
A
chromogranin
synaptophysin
NCAM
*CD56
TTF1
3
Q
Paraneoplastic syndromes associated with SCLC
A
Limbic encephalitis
SIADH
LEMS
Cortico-cerebellar degeneration
Cushings
4
Q
Clinical benefit of PCI in SCLC
A
OS benefit
5
Q
1) Surgically resectable SCLC based on stage 2) surgery type
A
1) I-IIA 2) Lobectomy
6
Q
Second line for SCLC
A
- IF relapse >6 months, rechallenge platinum/etoposide
IF relapse <6 months, lurbinectedin vs. topotecan
7
Q
What is resectable disease in limited stage small cell
A
no hilar or mediastinal lymph node involvement
8
Q
Suprahilar edema post LS SCLC management
A
observation (radiation SE)
