SB3e Genetic Variants Flashcards
1
Q
what causes a mutation?
A
a change in bases of a gene
2
Q
what causes a change in bases of a gene?
A
when DNA is not copied correctly in cell division or by environmental factors
3
Q
alleles?
A
different forms of each gene
4
Q
what are your characteristics determined by?
A
the alleles you inherit
5
Q
what four polypeptides does haemoglobin contain?
A
two a and two B
6
Q
what is haemoglobin?
A
a spherical protein that carries oxygen
7
Q
what do RNA polymerase attach to?
A
DNA bases in front of the gene
8
Q
a mutation in RNA polymerase attaching to DNA bases can prevent….
A
RNA polymerase binding correctly, reducing transcription and can cause B-thalassaemia
9
Q
what is B-thaassaemia?
A
lack of B-polypeptide
10
Q
symptoms of B-thalassaemia? 3
A
~weakness
~shortness in breath
~tiredness
