save my exams cell membrane and trasnport Flashcards
luid mosaic model also helps to explain:
Passive and active movement between cells and their surroundings
Cell-to-cell interactions
Cell signalling
Phospholipids
The phosphate head of a phospholipid is polar (hydrophilic) and therefore soluble in water
The lipid tail is non-polar (hydrophobic) and insoluble in water
phospholipid monolayer
phospholipids are spread over the surface of water they form a single layer with the hydrophilic phosphate heads in the water and the hydrophobic fatty acid tails sticking up away from the water
micelle
If phospholipids are mixed/shaken with water they form spheres with the hydrophilic phosphate heads facing out towards the water and the hydrophobic fatty acid tails facing in towards each other
proteins in membrane
proteins can either be intrinsic or extrinsic
intrinsic
are embedded in the membrane with their arrangement determined by their hydrophilic and hydrophobic regions
Extrinsic proteins
found on the outer or inner surface of the membrane
why fluid mosiac is fluid
The phospholipids and proteins can move around via diffusion
The phospholipids mainly move sideways, within their own layers
The many different types of proteins interspersed throughout the bilayer move about within it
fluid mosaic mosaid bc
The scattered pattern produced by the proteins within the phospholipid bilayer looks somewhat like a mosaic when viewed from above
three types of lipids
Phospholipids
Cholesterol
Glycolipids
two types of proteins
Glycoproteins (also containing carbohydrates)
Other proteins (eg. transport proteins)
phospholipids jobs
Form a bilayer
Hydrophobic tails point in towards the membrane interior
Hydrophilic heads point out towards the membrane surface
Individual phospholipid molecules can move around within their own monolayers by diffusion
cholestrol
Cholesterol molecules also have hydrophobic tails and hydrophilic heads
Fit between phospholipid molecules and orientated the same way (head out, tail in)
Are absent in prokaryotes membranes
glycolipidds
These are lipids with carbohydrate chains attached
These carbohydrate chains project out into whatever fluid is surrounding the cell
glycoproteins
These are proteins with carbohydrate chains attached
These carbohydrate chains also project out into whatever fluid is surrounding the cell
proteins
proteins embedded within the membrane are known as intrinsic proteins
transmembrane proteins
Transport proteins
extrinsic proteins
extrinsic proteins
Proteins can also be found on the inner or outer surface of the membrane
transport proteins
are an example of transmembrane proteins as they cross the whole membrane
transmembrane proteins
Most commonly, they span the entire membrane
phospholipid bilayer structure
tails form a hydrophobic core comprising the innermost part of both the outer and inner layer of the membrane
barrier to most water-soluble substances
ensures water-soluble molecules such as sugars, amino acids and proteins cannot leak out of the cell
what do cholestrols do
regulates the fluidity of the membrane
sit in between the phospholipids, preventing them from packing too closely together
nteraction between cholesterol and phospholipid tails also stabilises the cell membrane at higher temperatures by stopping the membrane from becoming too fluid
what glycoproteins and glycolipids do
contain carbohydrate chains that exist on the surface enables them to act as receptor molecules
allows glycolipids and glycoproteins to bind with certain substances at the cell’s surface