save my exams cell membrane and trasnport Flashcards

1
Q

luid mosaic model also helps to explain:

A

Passive and active movement between cells and their surroundings
Cell-to-cell interactions
Cell signalling

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2
Q

Phospholipids

A

The phosphate head of a phospholipid is polar (hydrophilic) and therefore soluble in water
The lipid tail is non-polar (hydrophobic) and insoluble in water

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3
Q

phospholipid monolayer

A

phospholipids are spread over the surface of water they form a single layer with the hydrophilic phosphate heads in the water and the hydrophobic fatty acid tails sticking up away from the water

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4
Q

micelle

A

If phospholipids are mixed/shaken with water they form spheres with the hydrophilic phosphate heads facing out towards the water and the hydrophobic fatty acid tails facing in towards each other

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5
Q

proteins in membrane

A

proteins can either be intrinsic or extrinsic

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6
Q

intrinsic

A

are embedded in the membrane with their arrangement determined by their hydrophilic and hydrophobic regions

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7
Q

Extrinsic proteins

A

found on the outer or inner surface of the membrane

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8
Q

why fluid mosiac is fluid

A

The phospholipids and proteins can move around via diffusion
The phospholipids mainly move sideways, within their own layers
The many different types of proteins interspersed throughout the bilayer move about within it

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9
Q

fluid mosaic mosaid bc

A

The scattered pattern produced by the proteins within the phospholipid bilayer looks somewhat like a mosaic when viewed from above

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10
Q

three types of lipids

A

Phospholipids
Cholesterol
Glycolipids

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11
Q

two types of proteins

A

Glycoproteins (also containing carbohydrates)
Other proteins (eg. transport proteins)

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12
Q

phospholipids jobs

A

Form a bilayer
Hydrophobic tails point in towards the membrane interior
Hydrophilic heads point out towards the membrane surface
Individual phospholipid molecules can move around within their own monolayers by diffusion

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13
Q

cholestrol

A

Cholesterol molecules also have hydrophobic tails and hydrophilic heads
Fit between phospholipid molecules and orientated the same way (head out, tail in)
Are absent in prokaryotes membranes

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14
Q

glycolipidds

A

These are lipids with carbohydrate chains attached
These carbohydrate chains project out into whatever fluid is surrounding the cell

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15
Q

glycoproteins

A

These are proteins with carbohydrate chains attached
These carbohydrate chains also project out into whatever fluid is surrounding the cell

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16
Q

proteins

A

proteins embedded within the membrane are known as intrinsic proteins
transmembrane proteins
Transport proteins
extrinsic proteins

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17
Q

extrinsic proteins

A

Proteins can also be found on the inner or outer surface of the membrane

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18
Q

transport proteins

A

are an example of transmembrane proteins as they cross the whole membrane

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19
Q

transmembrane proteins

A

Most commonly, they span the entire membrane

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20
Q

phospholipid bilayer structure

A

tails form a hydrophobic core comprising the innermost part of both the outer and inner layer of the membrane
barrier to most water-soluble substances
ensures water-soluble molecules such as sugars, amino acids and proteins cannot leak out of the cell

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21
Q

what do cholestrols do

A

regulates the fluidity of the membrane
sit in between the phospholipids, preventing them from packing too closely together
nteraction between cholesterol and phospholipid tails also stabilises the cell membrane at higher temperatures by stopping the membrane from becoming too fluid

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22
Q

what glycoproteins and glycolipids do

A

contain carbohydrate chains that exist on the surface enables them to act as receptor molecules
allows glycolipids and glycoproteins to bind with certain substances at the cell’s surface

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23
Q

what transport proteins do

A

create hydrophilic channels to allow ions and polar molecules to travel through the membrane.

24
Q

two types of tansport proteins

A

channel (pore) proteins
carrier proteins

25
3 main receptor types
signalling receptors for hormones and neurotransmitters receptors involved in endocytosis receptors involved in cell adhesion and stabilisation
26
facillitated diffusion
Certain substances cannot diffuse through the phospholipid bilayer of cell membranes. These include: Large polar molecules such as glucose and amino acids Ions such as sodium ions (Na+) and chloride ions (Cl-) These substances can only cross the phospholipid bilayer with the help of certain proteins This form of diffusion is known as facilitated diffusion There are two types of proteins that enable facilitated diffusion: Channel proteins Carrier proteins They are highly specifi
27
channel proteins
water-filled pores allow charged substances (eg. ions) to diffuse through the cell membrane part of the channel protein on the inside surface of the membrane can move in order to close or open the pore allows the channel protein to control the exchange of ions
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carrier proteins
carrier proteins can switch between two shapes binding site of the carrier protein to be open to one side of the membrane first, and then open to the other side of the membrane when the carrier protein switches shape down a concentration gradient
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factors affecting diffusion
steepness of conc gradient temperature surface area properties of molecules of ions
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steepness of conc gradient
-greater difference in conc means a greater difference in the number of molecules passing in the two directions and therefore a faster rate of diffusions
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temperature
molecules and ions have more kinestic energy at a higher temperatures they move faster resulting in higher rate of diffusuion
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surface area
greater surface area across which diffusion is taking place the greater the number of molecules or ions that can cross it any one moment and therefore that faster diffusion occurs
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properties of molcules or ions
-large molecules diffuse more slowly than smallerones as they require more energy to move uncharged non polar moles mdiffuse directly across phospholipid bilayer
34
def of osmosis
net movement of water molecules from a region of higher water potential (dilute solution) to a region of lower water potential (concentrated solution), through a partially permeable membrane
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water potential
tendency of water to move out of a solution. This term is used to avoid confusion between water concentration and concentration of a solution
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dilute and conc sol
A dilute solution has a high water potential (the right-hand side of the diagram below) and a concentrated solution has a low water potential
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what happens during osmosis
diffusion of water molecules from a dilute solution (high concentration of water) to a more concentrated solution (low concentration of water) across a partially permeable membrane In doing this, water is moving down its concentration gradient The cell membrane is partially permeable which means it allows small molecules (like water) through but not larger molecules (like solute molecules)
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plasmolysis of a plant cells placed in sol w lower water potential
1)turgid cell showing partially permeabe membrsnes as dotted lines 2)plasmlysis in progress water leaves the plant cell by osmosis- protoplast is starting to shrink away from the cell wall 3)fully plasmolysed cell and protoplast has shrunk away from the cell wall and the cell is fully plasmolysed
39
plate in pure water or dilute
water will enter the plant cell through its partially permeable cell surface membrane by osmosis, as the pure water or dilute solution has a higher water potential than the plant cell volume of the plant cell increases expanding protoplast pressure builds up inside the cell stops too much water entering and this also helps to prevent the cell from bursting turgid
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hypertonic rbs
-rbc have a higher water potential than solution so net movement of water out and cell shrivels
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isotonic rbc
-water potential equal between rbc and solution -no net movement of water -nromal cells
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hypotonic solutions
-red blood.cells have lower water potential than solution -net movement of water in -cells swell and may burst
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why osmosis more severe in animals than plants
As animal cells do not have a supporting cell wall (unlike plant cells), the results of this loss or gain of water on the cell are more severe
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animal in lower water potetnial
such as a concentrated sucrose solution), water will leave the cell through its partially permeable cell surface membrane by osmosis and the cell will shrink and shrivel up This occurs when the cell is in a hypertonic environment (the solution outside of the cell has a higher solute
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hypotonic
placed in pure water or a dilute solution, water will enter cell will continue to gain water by osmosis until the cell membrane is stretched too far and the cell bursts no cell wall the solution outside of the cell has a lower solute concentration than the inside of the cell)
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active transport
movement of molecules and ions through a cell membrane from a region of lower concentration to a region of higher concentration using energy from respiration
47
what is active trasnport important for
Reabsorption of useful molecules and ions into the blood after filtration into the kidney tubules Absorption of some products of digestion from the digestive tract Loading sugar from the photosynthesising cells of leaves into the phloem tissue for transport around the plant Loading inorganic ions from the soil into root hairs
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co transport
coupled movement of substances across a cell membrane via a carrier protein This means that two types of molecule are moved across the membrane at the same time; the movement of one is dependent on the movement of the other It involves a combination of facilitated diffusion and active transport
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what does active transport require
carrier proteins (each carrier protein being specific for a particular type of molecule or ion) requires energy to make the carrier protein change shape, allowing it to transfer the molecules or ions across the cell membrane
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specific co-transport protein is involved in the absorption of glucose and sodium ions as follows:
The active transport of sodium ions from the epithelial cell into the blood lowers the sodium ion concentration inside the cell and generates a sodium ion concentration gradient between the ileum and the epithelial cell Sodium ions move into the cell from the ileum by facilitated diffusion, carrying glucose molecules along with them via a cotransport protein The glucose concentration inside the epithelial cell increases, and glucose molecules enter the blood via facilitated diffusion
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two factors facillitated diffusion depends on
-conc gradient acorss exchange surface -number of channel or carrier proteins available in the exchange surface
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number of channel or carrier proteins available in the exchange surface
-uses channel and carrier proteins -once all the channel or carrrier protrins are in use the rate of facilliatated diffusion of a partifular moleule can no longer increase -greater number channel or carrier proteins availabe in the exchange surface the higher the fate of facillitated difusion
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neurones and muscle cellw
Are involved in the transmission of electrical impulses around the body They have cell membranes that contain channel proteins for sodium, potassium and calcium ions The opening and closing of these channel proteins (and the resulting facilitated diffusion of these different ions), as well as the number of these channel proteins, plays an important role in the speed of electrical transmission, both along the membranes of neurones (during nerve impulses) and in muscle cells (during muscle contraction)
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epethilial and small intestines
Have microvilli (highly folded sections of the cell membrane), which increases the cell’s surface area so the rate of diffusion of the products of digestion is greater (more particles can be exchanged in the same amount of time) Each villus of the small intestine has a constant blood supply, which continually transports the products of digestion away from the epithelial cells. This maintains a high concentration gradient across the epithelial cell exchange surface (between the lumen of the small intestine and the interior of the epithelial cell)
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root hair cells
Are adapted for the absorption of water and mineral ions from soil Have a specialised shape (the root ‘hair’) that increases the cell’s surface area so the rate of water uptake by osmosis is greater (can absorb more water and mineral ions than if the surface area was lower) Have thinner walls than other plant cells so that water can move through easily (due to shorter diffusion distance) Have a permanent vacuole containing cell sap, which is more concentrated than soil water. This ensures a high water potential gradient is maintained