Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Histopathology > SAS1: Introduction to Pathology > Flashcards

SAS1: Introduction to Pathology Flashcards

1
Q

Are the basic units of tissue, which form an organs and system in the human body?

A

Cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The two main types of body cell

A

Epithelial and Mesenchymal cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

A person to first published cellular theory of disease bringing in the concept that disease occur due to abnormalities at the levels of cell.

A

Virchow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Is defined as a variety forms of stresses a cell encounters as a result of changes in its internal external environment

A

Cell injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

The stress is mild to moderate, the cell injured may recover

A

Reversible Cell Injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The residual effects of reversible cell injury may persist in the cell as evidence of cell injury at subcellular level.

A

subcellular changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Metabolites may accumulate within the cell.

A

Intracellular accumulations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

The cells may be broadly injured by two major ways:

A

Genetic cause
Acquired cause

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Deficiency of oxygen result in failure to carry out activities of cells.

A

Hypoxia and Ischaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

The most common cause of cell injury.

A

Hypoxia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Reduced supply of blood to cells due to interruption ei. ischemia

A

Hypoxia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Physical agents in causation of disease is under ?

A

Mechanical Trauma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Trauma cause by heat or cold

A

Thermal Trauma: Physical Trauma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Trauma cause by ultraviolet and ionizing

A

Electricity; Radiation : Physical Trauma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

An ever increasing list of chemical agents and drugs may cause ,what type of cell injury?

A

Chemicals and Drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Injuries by microbes including infection caused by bacteria, rickettsiae, viruses, fungi, protozoa, metazoa and other parasites.

A

Microbial Agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Immunity is a double edge sword it protects the host against various injurious agents but also turns lethal and cause cell injury

A

Immunologic Agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

A deficiency or an excess of nutrients may result in nutritional imbalances, may be due to overall deficiency in nutrients.

A

Nutritional Derangements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Senescence leads to impaired ability of the cells to undergo replication and repair leading to cell death.

A

Aging

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Common acquires mental disease due to stress, strain, anxiety, overwork and frustration depression and schizophrenia.

A

Psychogenic Disease

21
Q

Anything that causes harm to the patient

A

Iatrogenic cause

22
Q

A cell injury that means “of unknown cause”

A

Idiopathic diseases

23
Q

one of the great Greek physicians, along with Erasistratus, provided a beginning for anatomical pathology and autopsy

A

Herophilus

24
Q

The replacement of one differentiated somatic cell type with another differentiated somatic cell type in the same tissue

A

Metaplasia

25
Q

Conversion in cell type

A

Metaplasia

26
Q

Occur in the epithelial and mesenchymal cells

A

Metaplasia

27
Q

It occur due to external stimulus

A

Metaplasia

28
Q

Reversible on withdrawal

A

Metaplasia

29
Q

Disorder cellular development

A

Dysplasia

30
Q

Changes in the phenotype cells

A

Dysplasia

31
Q

Occur due to the alteration of the genetic material

A

Dysplasia

32
Q

It may regress on removing the stimulus or may progress to high grade dysplasia

A

Dysplasia

33
Q

Various mechanisms which involved in adaptive cellular responses include the following:

A
  1. Altered cells surface receptor binding
  2. Alterations in signal for protein synthesis
  3. Synthesis of new proteins by the target cells such as heat shock proteins.
34
Q

Results in a build up of decomposing dead tissue and cell debris at or near the site of the cell death.

A

Untreated necrosis

35
Q

The death of body tissue.

A

Necrosis

36
Q

A procedure necessary to remove necrotic tissue surgically

A

debridement

37
Q

Types of Necrosis

A
  1. Coagulative necrosis
  2. Colliquative necrosis
  3. Caseous necrosis
  4. Gangrenous necrosis
  5. Fibrinoid necrosis
  6. Fat necrosis
38
Q

Formation of a gelatinous substance in dead tissues in which the architecture of the tissue is maintained and can be observed by light microscopy. Occurs as the result of protein denaturation causing albumin to transform into firm and opaque state.

A

Coagulative necrosis

39
Q

Cell undergo lysis rapidly in contrast to coagulative necrosis, is characterized by the digestion of dead cells to form a viscous liquid mass.

A

Colliquative

40
Q

Infection with Mycobacterium tuberculosis which interacts with macrophages. The necrotic tissue appears white and friable, like clumped cheese.

A

Caseous Necrosis

41
Q

Necrosis to the appendage. Usually the limbs

A

Gangrenous Necrosis

42
Q

Is a special form of necrosis usually caused by immune mediated vascular damage smooth muscle necrosis, fibrin release ( malignant Hypertension)

A

Fibrinoid Necrosis

43
Q

Is a specialized necrosis of fat tissues resulting from the action of activated lipase on fatty tissue such as the pancreas

A

Fat Necrosis

44
Q

Nuclear changes related to necrosis

A
  1. Margination of chromatin
  2. Pyknosis
  3. Karyolysis
  4. Karyorrhexis
45
Q

Chromatin condensing around the periphery of the nucleus

A

Margination of chromatin

46
Q

Small and dense nuclei

A

Pyknosis

47
Q

Complete lysis of the nuclei

A

Karyolysis

48
Q

Nuclei fragmentation ( generally seen in apoptosis)

A

Karyorrhexis

Histopathology (22 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions