Cytopathology Part II Flashcards
Better to differentiate between mesothelioma & metastatic carcinoma by using
special stains & immunohistochemistry.
Reactive, Malignant, Adenocarcinoma:
Clear, turbid
Reactive
Mesothelial Cells
Reactive, Malignant, Adenocarcinoma:
Always hemorrhagic
Malignant
Mesothelioma
Reactive, Malignant, Adenocarcinoma:
Hemorrhagic
Adenocarcinomas
(metastatic)
Reactive, Malignant, Adenocarcinoma:
Singly mainly, less as tissue fragments.
Ill defined cell borders.
Reactive
Mesothelial Cells
Reactive, Malignant, Adenocarcinoma:
Small to large complex sheets of cells.
Well defined cell borders.
Malignant
Mesothelioma
Reactive, Malignant, Adenocarcinoma:
Acinar (gland like formation).
Well defined cell borders.
Adenocarcinomas
(metastatic)
Reactive, Malignant, Adenocarcinoma:
Variable in number & shape. Normal N/C ratio Multiple micronucleoli.
Reactive
Mesothelial Cells
Reactive, Malignant, Adenocarcinoma:
Same
Increase N/C ratio
Malignant
Mesothelioma
Reactive, Malignant, Adenocarcinoma:
Single, macronucleoli, coarse chromatin.
Increase N/C ratio
Adenocarcinomas
(metastatic)
Reactive, Malignant, Adenocarcinoma:
Moderate to abundant cytoplasm
Reactive
Mesothelial Cells
Reactive, Malignant, Adenocarcinoma:
Scant to moderate amount.
Malignant
Mesothelioma
Reactive, Malignant, Adenocarcinoma:
Scant to moderate amount. Presence of cytoplasmic vacuoles & signet ring cells
Adenocarcinomas
(metastatic)
Offers highly diagnostic values for diagnosis of centrally
located lung cancer (Squamous, small cell cancers of lung).
Sputum Cytology
In how many days does sputum examinations is advisable to increase the rate of detection of cancers.
3 to 5 consecutive daily
Sputum sample is fixed with
Saccomanno fixative
Saccomanno fixative is composed of
2% polyethylene glycol With 50% ethyl alcohol
Sputum sample is considered satisfactory when it contains
alveolar macrophages
Benign pattern or Malignant pattern:
Almost low cellularity
Benign pattern
Benign pattern or Malignant pattern:
High cellularity
Malignant pattern
Benign pattern or Malignant pattern:
Sheets of uniform ductal cells (cohesive)
Benign pattern
Benign pattern or Malignant pattern:
Single, variable size malignant cells. (poorly cohesive)
Malignant pattern
Benign pattern or Malignant pattern:
Single bare nuclei: FREQUENT
Benign pattern
Benign pattern or Malignant pattern:
Single bare nuclei: ABSENT
Malignant pattern
Benign pattern or Malignant pattern:
Nuclear characteristics: Uniform size
Benign pattern
Benign pattern or Malignant pattern:
Nuclear characteristics: Enlarged, atypical nuclei
Malignant pattern
