salivary gland disorders and head and neck malignancy

Question 1

acute, subacute or chronic inflammation of the salivary glands

Answer 1

sialadenitis

Question 2

acute sialadenitis can be due to either a an infectious or inflammatory disorders of the salivary glands

1. viral cause
2. bacterial cause

Answer 2

1. viral- mumps

2. bacterial- staph. aureus

Question 3

mumps is considered an epidemic parotiditis

1. caused by which virus
2. complications include

Answer 3

1. myxovirus

2. complications include sensorineural deafness

Question 4

chronic sialadenitis is usually caused by

Answer 4

scarring and inflammation of the duct and/or parenchyma

Question 5

sialolithiasis

1. gland involved
2. etiology
3. clinical
4. associated with

Answer 5

1. submandibular&raquo_space; parotid
2. inspirated secretions, ductal debris, and calcium phosphate coalesce
3. recurrent episodes of pain and swelling
4. associated with infections due to stasis

Question 6

mosto common benign lesion of the salivary gland. occurs most frequent in the lower lip and oral cavity often due to trauma

Answer 6

mucocele

Question 7

immunologically-mediated destruction of the salivary gland and lacrimal gland

Answer 7

sjorgen syndrome

Question 8

sjorgen syndorme

1. most common in
2. symptoms
3. diagnosis
4. ab are
5. findings (2)

Answer 8

1. in middle age women
2. dry eyes and dry mouths
3. biposy of the lower lip
4. ab are SS-A (Ro) and SS-B (La) and ANCA test is positive in 50%
5. findings: (1) CD4 T cells (2) ductal epithelial hyperplasia

Question 9

Pleomorphic adenoma

1. benign/malignant
2. location
3. symptoms
4. occurs in
5. histo

Answer 9

1. benign
2. most common site is the tail of the parotid
3. usually painless it grows slowly
4. females>males
5. histo: admixture of epithelial, myoepithelial and stromal in a fibrous capsule

Question 10

warthin tumor

1. benign/malignant
2. occurs in
3. location
4. associated with
5. histo

Answer 10

1. benign
2. males>females
3. parotid
4. smoking
5. papillary structure and mature lymphocytes

Question 11

Mucoepidermoid carcinoma

1. benign/malignant
2. occurs in
3. location
4. symptoms
5. histo

Answer 11

1. malignant
2. children
3. parotid
4. variable- some are painless and slow growing other are painful and high grade
5. mixture of squamous, mucus-secreting cells and intermediate cells

Question 12

Head and neck squamous cell carcinoma:

1. common
2. sites
3. associated with

Answer 12

1. > 95% of head and neck cancers are HNSCC
2. common sites: ORAL CAVITY: ventral tongue, floor of mouth, lower lip, soft palate, gingiva
3. HPV

Question 13

a precursor lesion of oral squamous cell carcinoma

Answer 13

leukoplakia

Question 14

differences btw HPV negative and HPV positive:

1. location
2. age
3. risk factors
4. incidence
5. survival

Answer 14

1. location: (+) tonsil and base of tongue (-) all sites
2. age : (+) younger (-) older
3. risk factors: (+) sexual behavior (-) smoking and alcohol
4. incidence: (+)increasing (-) decreasing
5. survival: (+) improved (-) unchanged