Salivary Gland and Saliva formation Flashcards
there are ____ pairs of salivary glands that produce the majority of our saliva
3 pairs
parotid ductt is called _____. it leaves te gland and pierces through fat and muscle to open into the mouth across from the second upper molar
stenson’s duct
submandibular duct is called _______. opens just under the tongue in the floor of the mouth
wharton’s duct
the average volume of saliva secreted in a 24 hr period is
1-1.5 liters
*most of which is secreted during meals
begins carbohydrate digestion and is inactivated by low pH
alpha amylase
begins lipid digestion by converting triglycerides to fatty acids and monoglycerides
lipase
important in bolus formation and swallowing food being ingested
mucin
is secreted by the HCO3-/Cl- exchanger that helps maintain a neutral pH in gland and mouth
HCO3-
taken up by various transporters/channels
Na+
salivary fluid is largely dependent upon _______ signaling from parasympathetic nerves while the protein content of saliva is by sympathetic nerves releasing of _______
salivary fluid is largely dependent upon cholinergic signaling from parasympathetic nerves while the protein content of saliva is by sympathetic nerves releasing of norepinephrine
reflex salivary gland secretion due to positive conditioning
nausea
ion concentration along the gland/duct
starts off isotonic in the acinus and becomes hypotonic
as water is lost through aquaporins channels it maintains isotonicity but then as it reaches the duct, AQP are lost and no longer water following ions
the majority of salivary ductal cells do not express AQP channels and are impermanent to water. without this feature it would be impossible to produce hypotonic saliva
yep
sodium removal from saliva by ductal epithelial cells is effected by the
flow rate
GI hormones play a role in the regulation of salivary secretion
nope