review Flashcards
nocturnal diarrhea
organic caused not a functional problem but more of an inflammatory issue
inflammatory diarrhea usually presents with
bloody diarrhea except microscopic colitis which is inflammatory but does not present with blood
ways to identify causes of inflammatory diarrhea
stool cultures and colonoscopy w/ biopsys
diarrhea that will slow down if you dont eat
osmotic
diarrhea will not slow down with absence of eating
secretory
carcinoid syndrome is only present when
mets it reaches the liver.
identifying osmotic vs secretory
using the fecal osmotic gap:
osmotic > 125
secretory <50
electrolytes form a major role in this type of diarrhea
secretory
ways to identify steathorrea
- stool for detection of fat
- fecal elastase- pancreatic insufficiency
- serum IgA TTG- celiac
secretin stimulation test
invasive test for checking pancreatic insufficiency since secretin stimulates bicarb release… very sensitive test
NOD2 and CARD15
genetic susceptibility to crohs disease that involves the ileum
IBD is due to a
chronic inflammation mediator imbalance such as TNA-alpha and IL-12 that are elevated pro-inflammatory agents
UC will present with what type of diarrhea
bloody
complication seen only in UC and not in CD
toxic megacolon
long term of UC consequence
colon cancer; risk increases with years and surveillance is needed
microscopic colitis
possible drug induced chronic inflammation disorder of the colon