digestion and absorption Flashcards

1
Q

main organ of digestion and absorption

A

small intestine

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2
Q

how much ml os lost each day in the stool?

A

100ml

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3
Q

are invaginations of the epithelium between the vili and are lined largely with younger epithelial cells

A

crypts

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4
Q

peptidases

A

cleave peptides to amino acids

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5
Q

enterocyte process and transport (4)

A
  1. aa
  2. glucose
  3. monoglycerides
  4. membrane enzymes
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6
Q

enteric endocrine cell involved with (3)

A
  1. gastrin
  2. cck
  3. secretin
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7
Q

paneth cell release

A

lysozyme which protects against bacterial infections

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8
Q

surface area of small intestine

A

largeeeeeeee due to the microvilli approx. the size of half of a basketball court

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9
Q

area where partially digested food from the stomach (chyme) is mixed with bile and pancreatic enzyme

A

duodenum

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10
Q

area where the chyme undergoes the largest amount of digestion with significant amount of nutrient absorption

A

jejunum

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11
Q

are where large amounts of nutrients are absorbed before emptying into the large intestine

A

ileum

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12
Q

mainly involved in the absorption of water and salts from the material that has not be digested. most digestion and nutrient absorption has already taken place

A

colon

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13
Q

most absorption of nutrients occurs along the entire small intestine with the exception of (3)

A
  1. iron- duodenum
  2. vit. B12- ileum
  3. Bile salts- ileum
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14
Q

in general, the digestive system is set up to maximize absorption; there is no regulation in the amount of substance absorbed into the body

A

yep

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15
Q

products of digestion are absorbed through the GI tract by (3)

A
  1. simple diffusion
  2. carrier method
  3. channel mediated
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16
Q

products of digestion goes to the vasculature/lymphatics

A

vasculature

17
Q

glucose, lactose and fructose transporters

A

glucose and lactose are transported by a Na+ dependent transported. Fructose uses a non-Na+ dependent transporter

18
Q

enterokinase

A

cleaves trypsinogen

19
Q

why are there are so many pancreatic proteases?

A

proteases cleave at specific a.a sites

20
Q

there are different transport aa into the enterocytes but the most common is the

A

sodium dependent co-transporter

21
Q

dietary fats are _____ that form micelles through pancreatic lipase to penetrate the unstirred layer adjacent to the small intestine epithelium and to be absorbed

A

triglycerides

22
Q

of particular importance in fat digestion and absorption are _____ which emulsify the fats allowing for their solution as micelles in chyme and increase/decrease the surface area on which the pancreatic lipases can operate

A

of particular importance in fat digestion and absorption are bile salts which emulsify the fats allowing for their solution as micelles in chyme and increase the surface area on which the pancreatic lipases can operate

23
Q

triglycerides enter the smooth endoplasmic reticulum where they are repackaged into ________ and then secreted into the vasculatures/lymphatics

A

triglycerides enter the smooth endoplasmic reticulum where they are repackaged into chylomicrons and then secreted into the lymphatics

24
Q

amount of water transported by each colon epithelial cells is much larger than that of the small intestinal cell

A

yep

25
Q

absorption of aa/simple sugars vs fatty acids/ glycerol

A

aa/ simple sugars are absorbed through membrane channels or transported while fatty acids and glycerol are absorbed directly

26
Q

of all the digestive enzymes only stomach and pancreatic proteases need to be

A

activated

27
Q

all the intestinal digestive enzymes are bound how?

A

membrane bound to the enterocyte apical membrane