Rhinovirus Flashcards
1
Q
Microbiology of RHinovirus
A
Non-enveloped, Positive RNA virus
2
Q
Where is Rhinovirus typically found
A
nasopharynx
3
Q
Why can’t it live in the LRT or GI
A
LRT is too hot, GI is too acidic
4
Q
Rhinovirus serotype is based on?
A
Receptor specificity
5
Q
The three serotypes are, ICAM-1, LDL-R, SIaloprotein receptors
A
truth
6
Q
WHat is the main virulence factor in Rhinovirus
A
Viral protease
7
Q
What does the viral protease do
A
Binds the CAP binding complex of euk cells and shuts off protein synthesis
8
Q
What allows RV to still replicate using host machinery after cleaving the CAP binding complex with viral protease>
A
IRES
9
Q
If fever is present….
A
Its probably not RV
