Pulmonary Neoplasms

Question 1

What form of lung cancer is most prevalent in women smokers

Answer 1

Adenocarcinoma

Question 2

Where is adenocarcinoma generally found in regards to the geography of the lung?

Answer 2

Periphery

Question 3

What is a subtype of adenocarcinoma

Answer 3

Bronchioalveolar carcinoma

Question 4

What represents about 20% of lung cancer in the US

Answer 4

Squamous cell carcinoma

Question 5

Where does squamous cell carcinoma most frequently occur?

Answer 5

In one of the larger bronchi (more central)

Question 6

WHo does squamous cell carcinoma most frequently affect

Answer 6

men and older folks of both genders

Question 7

What lung cancer has the highest likelihood of metastasis

Answer 7

Small cell, then large cell

By the time small cell carcinoma is diagnosed it has virtually always metastasized already

Question 8

“scar carcinoma”

Answer 8

Adenocarcinoma

Question 9

Adenocarcinoma derived from bronchioles or alveolar walls

Answer 9

adenocarcinoma in situ

Question 10

Intrabronchial spread

Answer 10

adenocarcinoma in situ

Question 11

How would you describe the typical spread of bronchioalveolar carcinoma

Answer 11

multi-focal and bilateral. INTRABRONCHIAL SPREAD. The pt coughs and coughs up tumor cells, aspirates them, and the tumor cells seed wherever they land.

Question 12

Lepidic growth

Answer 12

adenocarcinoma in situ….classically climbs along the alveolar septa

Question 13

How do people with squamous cell carcinoma often die>

Answer 13

Massive hemorrhage. The tumor grows right next to the primary bronchus with is close to the pulmonary artery

Question 14

Keratin Pearl

Answer 14

Squamous cell

Question 15

Which type of cancer may produce hormones

Answer 15

neuroendocrine (small cell) Produces ACTH which causes Cortisol to be released

Question 16

Microscopic histology of small cell carcinoma

Answer 16

Nuclei are “molding around each other” virtually no cytoplasm in cells

Question 17

Definition of a paraneoplastic syndrome

Answer 17

a group of signs and symptoms caused by a substance that is produced by a tumor or in reaction to a tumor.

Question 18

Carcinoid tumors

Answer 18

represent 1-5% of all lung tumors, generally not related to smoking, generally due not secrete substances causing carcinoid syndrome, composed of nests of small round, uniform cells

Question 19

What is carcinoid syndrome

Answer 19

a group of symptoms associated with carcinoid tumors- tumors of the small intestine, colon, appendix, and bronchial tubes in the lungs. Most Carcinoid tumors have no symptoms. THey only produce the syndrome about 10% of the time. Symptoms are produced by the vasoactive effects of substances produced in the tumor:
Abdominal pain, bright red flsuhing of the face, diarrhea, heart palpitations, hypotension…can be brought on by eating bleu cheese, chocolate, or drinking red wine.

Question 20

Most common point of metastasis from the lungs to another body part

Answer 20

Brain

Question 21

Brain metastases from lung cancer are commonly

Answer 21

multiple and seen at the grey white junction

Question 22

Pleural mesotheliom

Answer 22

a malignant neoplasm of the pleura, related to asbestos exposure. 10% risk in heavily exposed individuals

Question 23

90% of mesotheliomas are asbestos related

Answer 23

true

Question 24

ship builder

Answer 24

asbestos exposure

Question 25

Smoking perpetuates the risk of bronchogenic carcinoma in asbetsos exposed individuals

Answer 25

truth

Question 26

Spindle like cells

Answer 26

mesothelioma