Rheumatology Flashcards

1
Q

Lower back and alternating buttock pain
Worse in the mornings
Disturbs the patient’s sleep

A

Ankylosing spondylitis

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2
Q

X ray in ankylosing spondylitis

A

syndesmophytes (fusion of vertebra)
Bamboo spine (fusion of spinal column)
squared vertebra

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3
Q

4 conditions associated with ankylosing spondylitis

A

anterior uveitis
upper lobe pulmonary fibrosis
inflammatory bowel disease
achilles tendonitis

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4
Q

Lace like rash on the back of the legs

A

Livedo reticularis
found in antiphospholipid syndrome

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5
Q

Mx of antiphospholipid syndrome

A

Warfarin
in pregnancy: LMWH + aspirin

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6
Q

Gout and common Px

A

uric acid buildup
paintful MTP joint in the big toe, red, swollen

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7
Q

Pseudogout cause and Ix

A

calcium pyrophosphate crystal buildup
Positive rhomboid

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8
Q

Px and Ix of churg-strauss syndrome

A

eosinophilic granulomatosis with polyangiitis
rash, asthma
raised eosinophils
pANCA positive

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9
Q

Px and Ix of Wegener’s granulomatosis

A

Granulomatosis with polyangiitis
1. URT: epistaxis’s saddle shaped nose
2. LRT: haemoptysis, dyspnoea
3. glomerulonephritis: proteinuria (frothy urine) + haematuria
cANCA +

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10
Q

Mx of Giant Cell Arteritis

A

oral prednisolone

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11
Q

Px of Rheumatoid arthritis

A

swan neck deformity, boutonnieres hand, C spine involvement
morning stiffness that is better after activity

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12
Q

Px of reactive arthritis

A

conjunctivitis
urethritis
arthritis

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13
Q

pregnant woman with rhuematoid. meds?

A

hydroxychloroquine, sulfasalazaline, folic acid

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14
Q

GCA mx

A

oral prednisolone if no visual compromise
IV methylprednisolone if there is visual compromise

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15
Q

antibody in SLE

A

anti ds DNA

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16
Q

antibody in polymyositis/dermatomyositis

A

anti Jo 1

17
Q

antibody in rheumatoid arthritis

A

Anti CCP

18
Q

autoimmune hepatitis antibody

A

anti smooth muscle

19
Q

antibody in cutaneous systemic sclerosis

A

anti centromere

20
Q

young, history of Hep B, systemic upset (CNS, GI, fever upset), nodular rash

A

polyarteritis nodosa

21
Q

Mx of polyarteritis nodosa

A

corticosteroids

22
Q

young woman presents acutely with blood pressure discrepancy, absent extremity pulses, fever, night sweats, limb claudication, stroke

A

takayasu’s arteritis

23
Q

what is sjogrens syndrome

A

decreased secretion production from lacrimal & salivary glands

24
Q

fatigue, dry mouth, dry eyes, dysapereunia,

A

sjogrens syndrome

25
Q

antibody in sjogrens

A

anti ro

26
Q

limited cutaneous systemic sclerosis acronym

A

CREST
calcinosis
raynauds
oesophageal dysmotility
sclerodactyly
telangectasia

27
Q

what is the key Ix in gout

A

joint aspiration to look for sodium monourate crystals

28
Q

key features of polymyositis

A

proximal muscle weakness (hip and shoulder girdle)
leads to respiratory and then pharyngeal muscles

29
Q

key features of dermatomyositis

A

same muscle weakness as polymyositis
heliotrope rash on eyelids
gottrons papules

30
Q

Mx of reactive arthritis

A

oral NSAIDs
then oral prednisolone

31
Q

Pt with diffuse systemic sclerosis
sudden headache, renal dysfunction
hypertension

what is it and MX???????

A

scleroderma renal crisis
1. ACEis
2. calcium channel blockers
3. dialysis

32
Q

Fetlys syndrome

A

rheumatoid arthrtiis
splenomegaly
neutropenia

33
Q

Difference between diffuse vs limited systemic sclerosis

A

Limited is hands, fingers, face
Diffuse is elbows, knees

34
Q

Polymyalgia rheumatica vs polymyositis

A

PMR is proximal joint pain and stiffness
Polymyositis is proximal muscle pain, raised myoglobin and creatine kinase

35
Q

what investigation to do when you suspect ankylosing spondylitis

A

pelvic MRI

36
Q

Antibody in diffuse systemic sclerosis

A

Anti scl 70

37
Q

causative agents of reactive arthritis

A

chlamydia
salmonella
shigella
campylobacter