Oncology Flashcards

1
Q

What is used to stage colorectal cancer

A

Dukes classification
A limited to bowel wall
B extends beyond the bowel wall
C lymph node
D distant metastasis

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2
Q

electrolyte abnormalities after chemotherapy

A

tumour lysis syndrome

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3
Q

Mx of tumour lysis syndrome

A

prophylactic allopurinol
Rasburicase to correct hyperuricaemia
Correct electrolyte abnormalities

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4
Q

features of sepsis after chemo, Mx

A

neutropenic sepsis. pip taz

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5
Q

mx of spinal cord compression

A

compression at a single level: neurosurgical decompression
compression at multiple levels: radiotherapy

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6
Q

hypercalcemia of malignancy mx

A

Iv sodium chloride 0.9%

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7
Q

Hyoscine butylbromide indications

A

Intestinal colic
Respiratory secretions

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8
Q

Gabapentin indications palliative care

A

Neuropathic pain

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9
Q

Mx of uncontrolled pain from bony metastasis

A

IV bisphosphonate e.g, ibandronate

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10
Q

lambert eaton syndrome associated with

A

carcinoma of bronchus

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11
Q

managment of anxiety and dyspnea

A

benzodiazepines e.g. midazolam

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12
Q

pathophis of hypercalcemia of malignancy

A

excessive PTHrP from solid tumours -> increases bone resorption and calcium absorption in the kidneys

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13
Q

Moa of allopurinol

A

Xanthine oxidase inhibitor
Prevents the conversion of purines into uric acid

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14
Q

palliative care nausea and vomiting management x 4 and MOA

A

cyclizine antimuscarinic
domperidone prokinetic
metaclopramide prokinetic
levomepromazine

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15
Q

Mx of respiratory secretions x 2 and difference

A

hyoscine hydrobromide (crosses the BBB so has a greater sedating and anti-emetic effect)

hyoscine butyl bromide (doesn’t cross the BBB)

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16
Q

Mx of breathlessness in palliative care

A

morphine

17
Q

Mx of pain in palliative care

A

oxycodone (if can’t tolerate opioids)
morphine
fentanyl (if can’t tolerate opioids)

18
Q

Mx of neuropathic pain 1st and 2nd line

A
  1. antidepressants and gabapentinoids
  2. ketamine
19
Q

what antiemetic shouldn’t be used in Parkinson’s and what should be used instead

A

don’t use metaclopramide
use domperidone

20
Q

glycopyrronium indication

A

noisy secretions at EOL

21
Q

haloperidol indication

A

nausea vomiting agitation delirium

22
Q

tumour marker for medullary thyroid cancer, where is it released from

A

calcitonin
released from C cells / parafollicular cells

23
Q

tumour marker for papillary and follicular thyroid cancer, where is it released from

A

thyroglobulin
released from thyroid follicular cells (epithelial cells)

24
Q

where are most zollinger Ellison gastrinomas found?

A

head of pancreas or 1st/2nd part of duodenum

25
Q
A