Rhabdomyolysis Flashcards
1
Q
What is rhabdomyolysis?
A
Rapid breakdown of skeletal muscle
2
Q
What can cause rhabdomyolysis?
A
Crush injury Strenuous exercise/activity e.g. seizure Medications- statins, diuretics, serotonin syndrome Drug abuse More..
3
Q
What s the presentation of rhabdomyolysis?
A
Dark brown urine AKI with disproportionately raised creatinine Muscle pain Weakness Vomiting Vonfusion
4
Q
What investigations are done for rhabdomyolysis?
A
Urinalysis- characteristic dark brown colour, haematuria
FBC, U&Es, Ca, ABG- AKI, CK >1000, hypocalcaemia, hyperphospataemia, hyperkalaemia, metabolic acidosis
5
Q
How is rhabdomyolysis managed?
A
Large volume IV fluids
Dialysis if required
6
Q
What is the management of hyperkalaemia?
A
IV calcium gluconate- stabilise myocardium
Insulin-dextrose
7
Q
What are the possible complications of rhabdomyolysis?
A
AKI
Elecyrolyte abnormalities
Metabolic acidosis
DIC
8
Q
What is the pathology within the kidneys?
A
Acute tubular necrosis
