Renal cancer Flashcards
What is the most common type of renal cancer?
Renal cell carcinoma
What are the types of renal cell carcinoma?
Clear cell= most common
papillary
Chromophobe
Bellini type ductal carcinoma
hat are the risk factors for renal cell carcinoma?
Middle aged men
Smoking
What is the presentation of renal cell carcinoma?
Asymptomatic Classic triad= flank pain, abdominal mass, hematuria Left varicocele Systemic symptoms Paraneoplastic syndromes
Why is left varicocele seen in renal cell carcinoma?
Obstruction of left renal vein
What paraneoplastic syndromes are seen in renal cell cancer?
Hypertension, hypercalcaemia
Abnormal LFTs
Polycythaemia
What investigations are done for renal cell carcinoma?
Bloods= FBC, U&Es, LFTs, Ca
CT chest and abdo
Renal tract US
What is the management of renal cell carcinoma?
Partial or total nephrectomy
Tyrosine kinase inhibitrs
Immunotherapy
What management options are not effective in renal cell carcinoma?
RAdiotherapy
Chemotherapy
What is nephroblastoma?
Rare tumour of childhood, usually presenting before age 4
What is the presentation of nephroblastoma?
Loin pain, haematuria Lethargy Pyrexia Early metastases
What is the management of nephroblastoma?
Nephrectomy
