Acute interstitial nephritis Flashcards
1
Q
What is acute interstitial nephritis known for?
A
Causes 25% of all drug induced AKIs
2
Q
What is the histology of acute interstitial nephritis?
A
Marked interstitial oedema and infiltrate in connective tissue between renal tubules
3
Q
What are the causes of acute interstitial nephritis?
A
Drugs= most common
Systemic disease
Infection
4
Q
What drugs can cause acute interstitial nephritis?
A
Panicillin NSAIDs Rifampacin Allopurinol Furosemide
5
Q
What is the presentation of acute interstitial nephritis?
A
Fever, rash, arthralgia
Renal impairment
Hypertension
6
Q
What investigations are done for acute interstitial nephritis?
A
Urinalysis= haematuria, sterile pyuria, white cell casts FBC= eosinophilia
7
Q
What is the management of acute interstitial nephritis?
A
Treat cause
Supportive