Retroviridae Flashcards
1
Q
Retro-: Etymology
A
Retro: Reverse transcription
2
Q
Retro-: Morphology
A
- Diploid +ssRNA
- Helical + icosahedral capsid
- Enveloped
3
Q
Retro-: Resistance
A
Very sensitive
4
Q
Retro-: Biological properties
A
- Baltimore VI - Viral reverse transcriptase → Integration
- Oncogenic
- Strong CPEs
5
Q
Retro-: Antigenic properties
A
- Good antigens
- Hypervariable surface antigens
- Igs not effective against the integrated virus
- Destruction of the immune system
- Cross reactions:
- Specificity of proteins
6
Q
Retro-: Diagnosis
A
- Clinical symptoms
- ELISA
- IF
- PCR
- NA hybridisation
- AGID
7
Q
Retro-: Genuses
A
- Orthoretrovirinae
- Alpharetrovirus
- Betaretrovirus
- Gammaretrovirus
- Deltaretrovirus
- Epsilonretrovirus
- Lentivirus (lentus-; slow)
- Spumaretrovirinae (spuma-: Foamy)
8
Q
Alpharetro-: Examples
A
- Avian leukosis virus
- Avian sarcoma leukosis virus
- Rous sarcoma virus
9
Q
Betaretro-: Examples
A
- Ovine pulmonary adenocarcinoma
- Mouse mammary tumour virus
- Monkey retrovirus
10
Q
Gammaretro-: Examples
A
- Feline, murine leukemia virus
- Viper retrovirus
- Reticuloendotheliosis virus
- Chick syncytial virus
- Duck spleen necrosis virus
11
Q
Reticuloendotheliosis virus
A
Chicken
- Immunosuppression
- Tumours
12
Q
Deltaretro-: Examples
A
- Bovine leukemia virus
- Human & primate T-lymphotropic virus 1-2
- Simian T-cell leukemia virus
13
Q
Bovine leukemia virus (BLV)
A
Cattle
- Leukosis
- Slow-developing lymphoid tumours
14
Q
Human T-Lymphotropic virus 1-2
A
Humans
- T-Cell leukemia
15
Q
Epsilonretro-: Examples
A
- Walleye dermal sarcoma virus
- Walleye epidermal hypoplasia virus
