Orthomyxoviridae

Question 1

Orthomyxo-: Etymology

Answer 1

Myxa-: Mucus

Question 2

Orthomyxo-: Morphology

Answer 2

• Segmented -ssRNA genome
• Helical capsid
• Enveloped

Question 3

Orthomyxo-: Resistance

Answer 3

Weak

Question 4

Orthomyxo-: Biological properties

Answer 4

• Baltimore V - Viral transcriptase
• Core protein
• Matrix protein
• Hemagglutinin (HA)
• Neuraminidase

Question 5

Orthomyxo-: Antigenic properties

Answer 5

• Antigenic drift: Mutations in the HA and NA antigens
• Antigenic Shift: Recombination resulting in new HA-NA combination

Question 6

Orthomyxo-: Diagnosis

Answer 6

• Isolation (embryonated egg)
• HA test
• Indirect: HAI

Question 7

Orthomyxo-: Genuses

Answer 7

• Influenza-A
• Influenza- B
• Influenza- C
• Isa-
• Thogoto-

Question 8

Influenza- A: Examples

Answer 8

Influenza: Human, equine, avian, porcine

“A heap”

Question 9

Influenza- B + C: Examples

Answer 9

• Human influenza
• B: Seals
• C: Dogs, swine

Question 10

Thogoto-

Answer 10

Tick-borne orthomyxo-like viruses

Question 11

Isavirus: Examples

Answer 11

Infectious salmon anemia virus

Question 12

Influenza- A: Symptoms

Answer 12

Fever, respiratory symptoms, muscle pains