Arena-, Bunya-, Borna- Flashcards by Oliver Woodroffe

Q

Mononegavirales consists of…

A

Bornaviridae
Arenaviridae
Rhabdoviridae
Filoviridae
Paramyxoviridae
Bunyaviridae

(BARF PB)

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Q

Bunya-: Etymology

A

Bunyamwera: African region

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Q

Bunya-: Morphology

A

Segmented -ssRNA genome
Helical capsid
Enveloped

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Q

Bunya-: Resistance

A

Weak

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Q

Bunya-: Biological properties

A

Baltimore V - Viral transcriptase
Zoonotic
Rodent reservoir

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Q

Bunya-: Antigenic properties

A

Good antigens
Cross-reaction within genera

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Q

Bunya-: Diagnosis

A

Isolation
IF
VN

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Q

Bunya-: Genuses

A

Orthobunya-
Hanta-
Nairo-
Phlebo-

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Q

Orthobunya-: Examples

A

Akabane virus
Lacrosse virus*
Tahyna virus*
Inkoo virus*

_{*Human - Fever, rash, encephalitis}

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Q

Phlebo-: Example

A

Rift valley fever virus

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Q

Nairo-: Examples

A

Nairobi sheep fever
Crimean-congo haemorrhagic fever

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Q

Hanta-: Example

A

Hantaan haemorrhagic fever with the renal syndrome

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Q

Arena-: Etymology

A

Arena-: Sand

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Q

Arena-: Morphology

A

Segmented -ssRNA genome
Øcapsid
Enveloped
Ribosomes inside

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Q

Arena-: Resistance

A

Weak

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Q

Arena-: Biological properties

A

Baltimore V - Viral transcriptase
Zoonotic
Rodent reservoir

Q

Arena-: Antigenic properties

A

Good antigens
Cross-reactions within the genus

Q

Arena-: Diagnosis

A

Isolation
IF
VN
IIF

Q

Arena-: Genuses

A

Old world
New world

Q

Arena-: Old world examples

A

Lymphocytic choriomeningitis virus
Lassa-, Mobala-, Mopeia-

Q

Arena-: New world example

A

Tacaribe-
Junin-
Machup-

Q

Rift valley fever virus

A

Sheep, cattle, zoonotic

Abortion
Fever
Blood
Diarrhoea

Mosquito transmitted

Q

Nairobi sheep fever

A

Sheep, goat

Fever
Abortion
High mortality

Tick transmitted

Q

Crimean-congo haemorrhagic fever

A

Humans

Haemorrhage
Rash
Nephritis

Q

Hantaan haemorrhagic fever

A

Human

Fever
Nephritis
High mortality

Rodent reservoir

Q

Lymphocytic choriomeningitis virus (LCM)

A

Europe, USA

Human (Pet hamsters → Children)

Paresis
Paralysis

Q

Lassa-; Mobala-; Mopeia virus

A

Africa

Humans, primates

Haemorrhage
Encephalitis

Q

Tacaribe-; junin-; Machup virus

A

S. America

Rodent → Human

Haemorrhage
Encephalitis

Q

Borna-: Morphology

A

-ssRNA genome
Helical capsid
Enveloped

Q

Borna-: Resistance

A

Weak

Q

Borna-: Biological properties

A

Baltimore V - Multiplication in the nucleus
Zoonotic
Rodent reservoir

Q

Borna-: Antigenic properties

A

Good antigens

Q

Borna-: Diagnosis

A

Clinical symptoms
Histopathology lesions
RT-PCR

Q

Borna-: Genus

A

Bornavirus

Q

Borna-: Examples

A

Bornavirus
Avian bornavirus

Q

Bornavirus

A

Euryxen

Encephalitis
Encephalosis (disease of brain)

Q

Avian bornavirus

A

Parrot

Proventricular dilation disease

Q

Bunya-: Transmission

A

Arbovirus (Except Hanta-)