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Poly- Papi- Adeno- Virus Flashcards

1
Q

Polyomaviridae: Etymology

A
  • Poly-: many
  • -oma: tumour
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2
Q

Polyomaviridae: Morphology

A
  • Circular dsDNA (Superhelical)
  • Icosahedral capsid
  • No envelope
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3
Q

Polyomaviridae: Resistance

A

Strong

56°C; 30 min; pH 3; lipid solvents

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4
Q

Polyomaviridae: Biological properties

A
  • Baltimore I - Cellular transcriptase
  • Oncogenic
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5
Q

Polyomaviridae: Antigenic properties

A

None

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6
Q

Polyomaviridae: Diagnosis

A
  • IF
  • EM
  • NA Hybridisation
  • HAI
  • PCR
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7
Q

Polyomaviridae: Genus

A

Polyomavirus

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8
Q

Polyomaviridae: Examples

A
  • Murine
  • Simian
  • Bovine
  • Goose
  • Human
  • BK virus
  • JC virus
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9
Q

BK virus

A

No clinical symptoms

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10
Q

JC virus

A

Demyelinisation in immunosuppressed patients

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11
Q

Polyomaviridae: General symptoms

A
  • Progressive multifocal leukoencephalopathy
  • Demyelination in immunosuppressed patients (fatal)
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12
Q

Papillomaviridae: Etymology

A
  • Papill-: wart
  • -oma: tumour
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13
Q

Papillomaviridae: Morphology

A
  • Circular dsDNA (Superhelical)
  • Icosahedral capsid
  • No envelope
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14
Q

Papillomaviridae: Resistance

A

Strong

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15
Q

Papillomaviridae: Biological properties

A
  • Baltimore I - Cellular transcriptase
  • Oncogenic
  • Stenoxenous
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16
Q

Papillomaviridae: Antigenic properties

A
  • Good antigens → Hidden
  • No cross-reactions
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17
Q

Papillomaviridae: Diagnosis

A
  • IF
  • EM
  • NA Hybridisation
  • Clinical signs
18
Q

Papillomaviridae: Genus

A

Papillomavirus

19
Q

Papillomaviridae: Examples

A
  • Papillomatosis: Equine, bovine, canine oral
  • Human (1-63)
20
Q

Papillomaviridae: Clinical symptoms

A

Warts, papillomas: Benignant tumours - pre-malignant status

21
Q

Equine papillomatosis

A
  • Head/nose
  • Transmission via:
    • Bit
    • Twitch
22
Q

Bovine papillomatosis

A
  • 1-6
  • Neck, back, body
23
Q

Canine oral papillomatosis

A
  • Oral mucosa
  • Epulis (Lump in gingival mucosa)
24
Q

Skin papillomas

A
  • Verruca vulgaris
    • Autosomal disorders & environmental factor → Squamous cell carcinomas
25
Q

Adenoviridae: Etymology

A

Adeno-: Adenoid gland

Lymphatic tissue between the back of the nose and the throat

26
Q

Adenoviridae: Morphology

A
  • Linear dsDNA
  • Icosahederal capsid
  • No envelope
27
Q

Adenoviridae: Resistance

28
Q

Adenoviridae: Biological properties

A
  • Baltimore I - Cellular transcriptase
  • Oncogenic
  • Stenoxenous
  • CPE: Nuclear inclusion bodies, rounding, lysis
29
Q

Adenoviridae: Antigenic properties

A
  • Good antigens
  • Cross-reactions
30
Q

Adenoviridae: Diagnosis

A
  • Isolation
  • AGP
  • VN
31
Q

Adenoviridae: Genuses

A
  • Adeno-:
    • Aviadeno-
    • Atadeno-
    • Mastadeno-
    • Siadeno-
32
Q

Mastadenovirus: Examples

A
  • Pneumoenteritis - Calves, lambs
  • Infectious canine hepatitis
  • Laryngotracheitis - Canine
  • Human adenovirus
33
Q

Canine laryngotracheitis

A

Kennel cough

34
Q

Human adenovirus

A

Military disease

35
Q

Aviadenovirus: Examples

A
  • CELO
  • GAL
    • Inclusion body hepatitis, Nephritis, Gizzard erosion
36
Q

Atadenovirus: Examples

A
  • Pneumoenteritis - Calves, lambs
  • Snake adenoviruses
  • Egg drop syndrome
37
Q

Siadenovirus: Examples

A
  • Haemorrhagic enteritis of turkey (marble spleen)
  • Frog adenovirus
38
Q

Ictadenovirus: Examples

A

Sturgeon adenovirus

39
Q

Polyoma-: Transmission

40
Q

Papilloma-: Transmission

A
  • Contact
  • Sexual

Virology (32 decks)

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