Poly- Papi- Adeno- Virus Flashcards
1
Q
Polyomaviridae: Etymology
A
- Poly-: many
- -oma: tumour
2
Q
Polyomaviridae: Morphology
A
- Circular dsDNA (Superhelical)
- Icosahedral capsid
- No envelope
3
Q
Polyomaviridae: Resistance
A
Strong
56°C; 30 min; pH 3; lipid solvents
4
Q
Polyomaviridae: Biological properties
A
- Baltimore I - Cellular transcriptase
- Oncogenic
5
Q
Polyomaviridae: Antigenic properties
A
None
6
Q
Polyomaviridae: Diagnosis
A
- IF
- EM
- NA Hybridisation
- HAI
- PCR
7
Q
Polyomaviridae: Genus
A
Polyomavirus
8
Q
Polyomaviridae: Examples
A
- Murine
- Simian
- Bovine
- Goose
- Human
- BK virus
- JC virus
9
Q
BK virus
A
No clinical symptoms
10
Q
JC virus
A
Demyelinisation in immunosuppressed patients
11
Q
Polyomaviridae: General symptoms
A
- Progressive multifocal leukoencephalopathy
- Demyelination in immunosuppressed patients (fatal)
12
Q
Papillomaviridae: Etymology
A
- Papill-: wart
- -oma: tumour
13
Q
Papillomaviridae: Morphology
A
- Circular dsDNA (Superhelical)
- Icosahedral capsid
- No envelope
14
Q
Papillomaviridae: Resistance
A
Strong
15
Q
Papillomaviridae: Biological properties
A
- Baltimore I - Cellular transcriptase
- Oncogenic
- Stenoxenous
16
Q
Papillomaviridae: Antigenic properties
A
- Good antigens → Hidden
- No cross-reactions