Herpes Virus Flashcards

1
Q

Herpesvirus: Morphology

A
  • Linear dsDNA
  • Icosahedral capsid
  • Enveloped
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2
Q

Herpesvirus: Resistance

A

Weak

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3
Q

Herpesvirus: Biological properties

A
  • Baltimore I - Cellular transcriptase
  • Oncogenic
  • Stenoxenous
  • Strong CPEs: Inclusion bodies, syncytia, rounding, lysis
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4
Q

Herpesvirus: Antigenic properties

A
  • Weak immunogens
  • Cross-reactions within genera
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5
Q

Herpesvirus: Diagnosis

A
  • Isolation
  • Co-cultivation
  • NA-hybridisation
  • PCR
  • VN for identification
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6
Q

Herpesvirus: Genuses

A
  • Alphaherpes-:
    • Mardi-
    • Varicello-
    • Ilto-
    • Simplex-
  • Betaherpes-
    • Muromegalo-
    • Cytomegalo-
    • Roseolo
  • Gammaherpes-
    • Ictaluri-
    • Lymphocrypto-
    • Rhadino-
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7
Q

Simplex-: Examples

A
  • Bovine herpesmamillitis
  • Simian herpes
  • Human herpes simplex
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8
Q

Human herpes simplex: Symptoms

A
  • Labial + genital lesions
  • Keratinitis
  • Encephalitis
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9
Q

Varicello-: Examples

A
  • Infectious bovine rhinotracheitis
  • Infectious pustular vulvovaginitis
  • Balanopostitis
  • Equine abortion/rhinopneumonitis
  • Coital exanthema
  • Pseudorabies - Aujeszky’s disease
  • Canine herpes virus
  • Feline rhinotracheitis
  • Human Varicella-Zoster
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10
Q

Mardivirus: Examples

A
  • Marek’s disease virus
  • Turkey herpesvirus
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11
Q

Cytomegalo-: Species affected

A
  • Human
  • Monkey
  • Elephant
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12
Q

Muromegalo-: Species affected

A

Mouse & rat

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13
Q

Probosci-: Example

A

Elephant cytomegalovirus

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14
Q

Roseolo-: Example

A

Human: Roseola infectosa

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15
Q

Gammaherpes-: Genuses

A
  • Lymphocrypto-
  • Rhadino-
  • Ictaluri-
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16
Q

Maca-, Peca-, Rhadinovirus: Examples

A
  • Rodent, ruminant herpesvirus
  • Human immunosuppressant patients
  • Bovine herpesvirus 4 - Pneumonia
  • Malignant catarrhal fever of cattle
  • Wildebeest, sheep - Symptomless cattle
  • Equid herpesvirus 2 & 5 - Foal pneumonia + Rh. equid
  • Kaposi’s sarcoma-associated herpesvirus
17
Q

Alloherpesviridae: Examples

A

Herpes: Koi, sturgeon, salmon

18
Q

Unassigned herpesviruses: Examples

A
  • Swine inclusion body rhinitis
  • Duck plague
  • Pigeon herpes
19
Q

Marek’s disease: symptoms

A
  • CNS symptoms
  • Paralysis
  • Lymphoid tumours
20
Q

Lymphocrypto-: Example

A
  • Epstein-Barr virus
  • Herpesvirus: Baboon, monkey, ape
21
Q

Rhadino-: Examples

A
  • Herpesvirus: Equid 2 & 5, bovine 4, ruminant, rodent
  • Kaposi’s sarcoma-associated herpesvirus
  • Malignant catarrhal fever of cattle