Course of infection Flashcards
1
Q
Give the parameters of viral infections
A
- Presence of infectious virions in the host
- Shedding of infective virions
- Clinical signs
- Immune response
2
Q
Title the figure
A
Timeline of acute infections
3
Q
X-axis title
A
Time
4
Q
y-Axis title
A
Titre
5
Q
A
Virus multiplication
6
Q
A
Shedding
7
Q
A
Clinical signs
8
Q
A
Immune response
9
Q
Give the outcomes of acute infections
A
- Recovery
- Death
- Chronic infection
10
Q
Title the figure
A
Chronic infections: Latent infection
11
Q
A
Reactivation
12
Q
Give the phases of latent infection
A
- Acute phase
- Latent phase
- Reactivation
- Immunosuppression
13
Q
List the types of chronic infection
A
- Acute
- Latent
- Tolerated
- Persisting
- Slow
14
Q
Title the figure
A
Tolerated infection
15
Q
Tolerated infection
A
- Infection at the 2nd trimester of pregnancy
- Self-recognition phase
- Virus antigen is regarded as own
- No immune response
- Continuous shedding
16
Q
Title the figure
A
Persisting infection
17
Q
Persisting infection
A
- Hidden neutralisation antigen
- Ig not active
- Clinical signs
- Immunocomplex deposition
- Hidden virus
- Equine arteritis
- Foot + mouth
- Canine distemper
18
Q
Title the figure
A
Chronic infections
19
Q
Slow infection
A
- Retroviruses
- Integration into the genome
- Antigenic changes
- Destruction of the immune system
- Prions
- Not immunogenic, usually no shedding in living animal
