Paramyxoviridae Flashcards

1
Q

Paramyxo-: Etymology

A
  • Para-: Like/near
  • Myxa-: Mucus
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2
Q

Paramyxo-: Morphology

A
  • -ssRNA
  • Helical capsid
  • Enveloped
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3
Q

Paramyxo-: Resistance

A

Weak

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4
Q

Paramyxo-: Biological properties

A
  • Baltimore V - Viral transcriptase
  • Hemagglutinin, neuraminidase
  • Fusion proteins
  • CPEs: Inclusion bodies, syncytia, hemadsorption
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5
Q

Paramyxo-: Antigenic properties

A
  • Good antigens
  • Cross-reactions within genera
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6
Q

Paramyxo-: Diagnosis

A
  • Isolation
  • HA
  • HAI
  • IF
  • VN
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7
Q

Paramyxo-: Genuses

A
  • Paramyxo-
    • Avula-
    • Respiro-
    • Morbilli-
    • Rubula-
    • Henipa-
  • Pneumovirinae
    • Metapneumovirus
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8
Q

Respiro-: Example

A
  • Parainfluenza- 1 (Human)
  • Parainfluenza- 3 (Shipping fever)
  • Sendai virus
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9
Q

Morbilli-: Examples

A
  • Canine + phocine distemper virus
  • Rinderpest virus
  • Measles
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10
Q

Rubula-: Examples

A
  • Mumps
  • Parainfluenza virus:
    • Simian
    • 2 (Kennel cough)
    • 4 (Human)
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11
Q

Avula-: Examples

A
  • Newcastle disease
  • Avian parainfluenza virus 2-9
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12
Q

Henipa-: Examples

A
  • Hendra virus
  • Nipah virus
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13
Q

Pneumo-: Examples

A
  • Murine pneumonia
  • Respiratory syncytial virus:
    • Human
    • Ovine
    • Bovine
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14
Q

Metapneumo-: Examples

A

Turkey rhinotracheitis virus (TRT)

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15
Q

Respiro-: Symptoms in humans

A
  • Fever
  • Influenza-like disease
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16
Q

Sendai virus

A

Rodents, rabbit

  • Pneumonia
  • Encephalitis
17
Q

Canine distemper virus

A

Canine

  • Acute fever & respiratory symptoms
  • Chronic encephalitis
18
Q

Phocine distemper virus

A

Seals

  • Fever
  • Pneumonia
19
Q

Rinderpest virus

A

Ruminants

  • Fever
  • Haemorrhage
  • Mucosal erosions
20
Q

Measles

A

Human

  • Fever
  • Rash
21
Q

Mumps

A

Human

  • Salivary gland swelling
  • Orchitis
  • Mastitis
  • Encephalitis
22
Q

Newcastle disease

A

Euryxen, Birds, Zoonosis

(Variants: Lento-; mezo-; velogen strains)

  • Viscerotrop form:
    • Haemorrhage
    • High mortality
  • Neurotrop form:
    • Encephalitis
23
Q

Hendra virus

A

Horse, human

  • Encephalitis
24
Q

Nipah virus

A

Swine, human

  • Encephalitis
25
Q

Bovine respiratory syncytial virus (RS)

A

Bovine

  • Pneumonia
  • Interstitial emphysema