Paramyxoviridae

Question 1

Paramyxo-: Etymology

Answer 1

• Para-: Like/near
• Myxa-: Mucus

Question 2

Paramyxo-: Morphology

Answer 2

• -ssRNA
• Helical capsid
• Enveloped

Question 3

Paramyxo-: Resistance

Answer 3

Weak

Question 4

Paramyxo-: Biological properties

Answer 4

• Baltimore V - Viral transcriptase
• Hemagglutinin, neuraminidase
• Fusion proteins
• CPEs: Inclusion bodies, syncytia, hemadsorption

Question 5

Paramyxo-: Antigenic properties

Answer 5

• Good antigens
• Cross-reactions within genera

Question 6

Paramyxo-: Diagnosis

Answer 6

• Isolation
• HA
• HAI
• IF
• VN

Question 7

Paramyxo-: Genuses

Answer 7

• Paramyxo-
  
  • Avula-
  • Respiro-
  • Morbilli-
  • Rubula-
  • Henipa-
• Pneumovirinae
  
  • Metapneumovirus

Question 8

Respiro-: Example

Answer 8

• Parainfluenza- 1 (Human)
• Parainfluenza- 3 (Shipping fever)
• Sendai virus

Question 9

Morbilli-: Examples

Answer 9

• Canine + phocine distemper virus
• Rinderpest virus
• Measles

Question 10

Rubula-: Examples

Answer 10

• Mumps
• Parainfluenza virus:
  
  • Simian
  • 2 (Kennel cough)
  • 4 (Human)

Question 11

Avula-: Examples

Answer 11

• Newcastle disease
• Avian parainfluenza virus 2-9

Question 12

Henipa-: Examples

Answer 12

• Hendra virus
• Nipah virus

Question 13

Pneumo-: Examples

Answer 13

• Murine pneumonia
• Respiratory syncytial virus:
  
  • Human
  • Ovine
  • Bovine

Question 14

Metapneumo-: Examples

Answer 14

Turkey rhinotracheitis virus (TRT)

Question 15

Respiro-: Symptoms in humans

Answer 15

• Fever
• Influenza-like disease

Question 16

Sendai virus

Answer 16

Rodents, rabbit

• Pneumonia
• Encephalitis

Question 17

Canine distemper virus

Answer 17

Canine

• Acute fever & respiratory symptoms
• Chronic encephalitis

Question 18

Phocine distemper virus

Answer 18

Seals

• Fever
• Pneumonia

Question 19

Rinderpest virus

Answer 19

Ruminants

• Fever
• Haemorrhage
• Mucosal erosions

Question 20

Measles

Answer 20

Human

• Fever
• Rash

Question 21

Mumps

Answer 21

Human

• Salivary gland swelling
• Orchitis
• Mastitis
• Encephalitis

Question 22

Newcastle disease

Answer 22

Euryxen, Birds, Zoonosis

(Variants: Lento-; mezo-; velogen strains)

• Viscerotrop form:
  
  • Haemorrhage
  • High mortality
• Neurotrop form:
  
  • Encephalitis

Question 23

Hendra virus

Answer 23

Horse, human

• Encephalitis

Question 24

Nipah virus

Answer 24

Swine, human

• Encephalitis

Question 25

Bovine respiratory syncytial virus (RS)

Answer 25

Bovine

• Pneumonia
• Interstitial emphysema