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My Cardiology > Reticuloendothelial System > Flashcards

Reticuloendothelial System Flashcards

1
Q

What are the lymphatic organs and tissues that make up the immune system

A

diffuse lymphatic tissue, lymphatic nodules, lymph nodes, spleen, bone marrow, tonsils and thymus

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2
Q

any substance that can induce a specific immune response

A

An antigen

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3
Q

What are the two type of immunity

A

Specific (adaptive) and non-specific (innate) immunity

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4
Q

Three types of phagocytic cells

A

macrophages, neutrophils, and monocytes

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5
Q

Three major types of lymphocytes

A

B cells, T cells, and NK cells

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6
Q

Which type of lymphatic tissue are found in the lamina propria of the alimentary canal, respiratory passages, and genitourinary tract

A

diffuse/mucosa-associated lymphatic tissue

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7
Q

Which type of lymphatic tissue is the site of the initial immune response

A

Diffuse lymphatic tissue

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8
Q

After lymphocytes get in contact with antigen in the diffuse lymphatic tissue, they travel to regional lymph nodes, proliferate and then return to the lamina propria as what kind of cells

A

B and T lymphocytes

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9
Q

True or False: diffuse lymphatic tissue commonly found in the walls of the alimentary canal, respiratory passages, and genitourinary tract and encapsulated

A

False

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10
Q

Which structure of the palatine tonsils contain numerous lymphatic nodules

A

Wall of the tonsillar crypts

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11
Q

Which three areas of the alimentary canal contain lymphatic nodules

A

palatine tonsils, payers patches in the ileum and the vermiform appendix

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12
Q

Which cell layer of the vermiform appendix contains lymphatic nodules

A

Lamina propria

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13
Q

True of false: lymph nodes are encapsulated

A

True

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14
Q

Three areas of the body where lymph nodes are concentrated

A

the axilla, groin, and mesenteries

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15
Q

Two types of lymphatic vessels serve the lymph node

A

Afferent and efferent lymphatic vessels

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16
Q

What are the supporting elements of the lymph node

A

capsule, trabeculae and reticular tissue

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17
Q

Cells of the Reticular Meshwork

A

reticular cells, dendritic cells, macrophages and follicular dendritic cells

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18
Q

what are the divisions of the parenchyma of the lymph node

A

cortex and medulla

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19
Q

Which portion of the cortex between the medulla and superficial cortex is free of nodules

A

deep cortex (paracortex)

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20
Q

Which region of a lymph node contains most of the T cells

A

deep cortex (paracortex)

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21
Q

Which region of the lymph node is also called the thymus-dependent cortex

A

deep cortex (paracortex)

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22
Q

The medulla of the lymph node consists of which structures

A

the medullary cords and medullary sinuses

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23
Q

which type of lymphocytes are conatined in the medullary cords

A

B lymphocytes

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24
Q

he site of fluid absorption and the entrance for circulating lymphocytes into the lymph node

A

Specialized high endothelial venules (HEVs)

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25
Q

Filtration of lymph in the lymph node occurs within a network of interconnected lymphatic channels called

A

sinuses

26
Q

The thymus is located in the

A

superior mediastinum

27
Q

The thymus is subdivided into ___________ by connective tissue

A

thymic lobules

28
Q

The extensive meshwork in the thymus is formed by what type of cells

A

epithelioreticular cells

29
Q

The thymic cortex is basophilic or acidophilic

A

basophilic

30
Q

What is the the largest lymphatic organ

A

Spleen

31
Q

Function of the spleen

A

filters blood and reacts immunologically to blood-borne antigens

32
Q

What type of cells are found in the spleen

A

lymphocytes, reticular cells, macrophages and dendritic cells

33
Q

What are the two subdivisions of the splenic pulp

A

white pulp and red pulp

34
Q

What does the white splenic pulp consist of

A

a thick accumulation of lymphocytes surrounding an artery

35
Q

What is the periarterial lymphatic sheath (PALS) in the spleen made up of

A

Lymphocytes that aggregate around the central artery

36
Q

What does the red splenic pulp consist of

A

large numbers of red blood cells that it filters and degrades

37
Q

What type of endothelial cells line splenic sinuses

A

very long, rod-shaped endothelial cells

38
Q

True or false: Splenic sinuses posses a continuous lamina

A

false

39
Q

What are the cells of the lymphoid system

A

Lymphocytes, macrophages, dendritic cells and reticular cells

40
Q

Which lymphocytes does humoral immunity

A

B lymphocyte

41
Q

Which lymphocyte does cellular immunity

A

T lymphocytes

42
Q

Which cells of the lymphoid system are phagocytic cells and antigen presenting cells

A

Macrophages and dendritic cells

43
Q

What is the purpose of primary lymphoid organs

A

They are a site for maturation and differentiation

44
Q

What is the purpose of secondary lymphoid organs

A

They are a site for interaction with antigens

45
Q

What are the primary lymphoid organs

A

Bone marrow and thymus

46
Q

What are the secondary lymphoid organs

A

Lymph node, spleen, tonsils

47
Q

Which other lymphoid tissue can be considered as primary

A

Gut Associated Lymphoid Tissue

48
Q

What are the two rounds of the selection that T-cells undergo during maturation

A

Positive- eliminates cells that cannot interact with self MHC molecules

Negative- eliminates cells that react against self epitopes

49
Q

Where in the thymus is there development of regulatory T cells

A

In the medulla

50
Q

What is the purpose of the development of regulatory T cells

A

to prevent autoimmune diseases

51
Q

Two functions of secondary lymphoid organs

A
  • Filters lymph - Helps activate the immune system
52
Q

What type of venules do lymph nodes have

A

high endothelial venules

53
Q

3 functions of the spleen

A

Filtration of blood

  • Phagocytosis of senescent RBCs and invading microorganisms
  • Proliferation of immunocompetent T and B lymphocytes.
54
Q

What does white pulp in the spleen consist of

A

White pulp consists of a thick accumulation of lymphocytes surrounding central artery

55
Q

What does white pulp in the spleen consist of

A

large numbers of RBCs that it filters and degrades

56
Q

Which part f the spleen contain splenic sinuses and cords

A

Red cords

57
Q

What shape endothelial cells line splenic sinuses

A

Rod shaped

58
Q

Tonsils are a ______ associated lymphatic tissue

A

Mucosa

59
Q

4 examples of mucosa associated lymphatic tissue

A
  • Peyer’s patches
  • Appendix
  • Tonsils
  • Lymphoid follicles in bronchi (BALT)
  • Lymphoid follicles in genitourinary organs
60
Q

What are the 4 tonsils

A
  • Palatine tonsils • Lingual tonsil

* Pharyngeal tonsil (adenoids) • Tubal tonsils

61
Q

Tonsils are covered by which type of epithelium

A

stratified squamous nonkeratinized epithelium

My Cardiology (21 decks)

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