Respiratory System- MoA Flashcards
1
Q
Beta-2 adrenergic agonists
A
Dilates bronchial smooth muscle
2
Q
Antimuscarinics
A
Blocks muscarinic acetylcholine receptors to promote bronchial dilation
3
Q
Methylxanthines
A
Bronchodilator, increases cAMP in smooth muscle via inhibition of phosphodiesterases
4
Q
Glucocorticoids
A
Reduction of inflammation and mucus production
5
Q
Leukotriene antagonists
A
Blockade of leukotriene receptors
6
Q
Dornase alfa
A
Synthetic DNAse 1 – breakdown of extracellular DNA to reduce
sputum viscosity
7
Q
Carbocisteine
A
cleavage of mucus glycoproteins to reduce sputum viscosity.