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Phase III: Drug List > Infections-MoA > Flashcards

Infections-MoA Flashcards

1
Q

Beta lactams (penicillins, carbapenems, cephalosporins)

A

Inhibition of bacterial cell wall synthesis

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2
Q

Trimethoprim

A

Inhibition of dihydrofolate reductase

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3
Q

Ciprofloxacin

A

Inhibition of bacterial DNA gyrase

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4
Q

Erythromycin, azithromycin

A

Inhibition of bacterial protein synthesis

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5
Q

Doxycycline, tetracycline

A

Inhibition of bacterial protein synthesis

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6
Q

Nitrofurantoin

A

Bacterial DNA interference

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7
Q

Gentamicin

A

Inhibition of bacterial protein synthesis

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8
Q

Vancomycin

A

Inhibition of cell wall synthesis in Gram-positive bacteria

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9
Q

Metronidazole

A

Inhibition of bacterial DNA synthesis

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10
Q

Isoniazid, ethambutol

A

Inhibition of mycobacterial cell wall synthesis

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11
Q

Rifampicin

A

Inhibition of mycobacterial RNA synthesis

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12
Q

Interferon alpha

A

Activation of antiviral intracellular and immune responses

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13
Q

Aciclovir, ganciclovir

A

Virus replication blockade

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14
Q

Oseltamivir

A

Prevention of viral budding and infectivity

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15
Q

Ribavirin

A

Disrupts viral RNA synthesis

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16
Q

Tenofovir

A

Blockade of viral reverse transcriptase function for viral genetic replication

17
Q

Lopinavir

A

Blockade of viral protease required for virus particle assembly

18
Q

Dolutegravir

A

Disrupts integration of HIV genome into host chromosomes

19
Q

Enfuvirtide

A

Blockade of virus fusion to target cell membrane

20
Q

Maraviroc

A

Blockade of HIV binding to co-factor for cell entry

21
Q

Triazole anti-fungal agent

A

Disruption of fungal membrane function

22
Q

Clindamycin

A

Inhibition of bacterial protein synthesis

23
Q

Gentamicin

A

Inhibition of bacterial protein synthesis

24
Q

Reverse transcriptase inhibitors

A

Blockade of viral reverse transcriptase function for viral genetic replication

25
Q

Ritonavir

A

Blockade of viral protease required for virus particle assembly

26
Q

Mebendazole

A

Disruption of microtubule assembly in helminth cells

27
Q

Permethrin

A

Inhibits invertebrate neural sodium channels, causing paralysis of pests

28
Q

Nevirapine

A

Blockade of viral reverse transcriptase function for viral genetic replication

Phase III: Drug List (48 decks)

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