Obstetrics, gynaecology and urinary-tract disorders- MoA Flashcards

1
Q

Desogestrel and ethinyl-estradiol

Etonogestrel

A

Mimics ovulation, reduces LH and FSH

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2
Q

Hormone replacement therapy (HRT)

A

Restores decreased hormone level and function

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3
Q

Dinoprostone

A

Prostaglandin E2- stimulates cervical ripening

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4
Q

Oxytocin

A

Stimulation of uterine contraction

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5
Q

Mifepristone with Misoprostol

A

Steroidal antiprogestogen in combination with synthetic prostaglandin

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6
Q

Tranexamic acid

A

Inhibits fibrin clot breakdown by plasmin

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7
Q

Mefenamic acid

A

Inhibition of prostaglandin synthesis

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8
Q

Tamsulosin

A

Smooth muscle relaxant acting on bladder neck

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9
Q

Urinary antispasmodics (antimuscarinic)

A

Blockade of acetylcholine receptors leading to bladder smooth muscle relaxation

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10
Q

Mirabegron

A

Stimulation of Beta-3 adrenergic receptors, leading to detrusor smooth muscle relaxation

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11
Q

Finasteride

A

Inhibition of synthesis of dihydrotestosterone

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12
Q

Oral combination pill contraceptives

A

Suppresses ovulation, reduces LH and FSH

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13
Q

Oral mini-pill contraceptives

A

Suppresses ovulation, reduces LH and FSH

Endometrial change, thickening of cervical mucus

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14
Q

Ulipristal

A

Stimulation of progesterone-like responses in pituitary and endometrium

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