Obstetrics, gynaecology and urinary-tract disorders- MoA Flashcards
Desogestrel and ethinyl-estradiol
Etonogestrel
Mimics ovulation, reduces LH and FSH
Hormone replacement therapy (HRT)
Restores decreased hormone level and function
Dinoprostone
Prostaglandin E2- stimulates cervical ripening
Oxytocin
Stimulation of uterine contraction
Mifepristone with Misoprostol
Steroidal antiprogestogen in combination with synthetic prostaglandin
Tranexamic acid
Inhibits fibrin clot breakdown by plasmin
Mefenamic acid
Inhibition of prostaglandin synthesis
Tamsulosin
Smooth muscle relaxant acting on bladder neck
Urinary antispasmodics (antimuscarinic)
Blockade of acetylcholine receptors leading to bladder smooth muscle relaxation
Mirabegron
Stimulation of Beta-3 adrenergic receptors, leading to detrusor smooth muscle relaxation
Finasteride
Inhibition of synthesis of dihydrotestosterone
Oral combination pill contraceptives
Suppresses ovulation, reduces LH and FSH
Oral mini-pill contraceptives
Suppresses ovulation, reduces LH and FSH
Endometrial change, thickening of cervical mucus
Ulipristal
Stimulation of progesterone-like responses in pituitary and endometrium