CV System- Adverse Effects/Interactions Flashcards

1
Q

Loop diuretics

A

Nausea, dizziness

NSAIDs, ACE inhibitors

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2
Q

Thiazides

A

Electrolyte imbalance, exacerbation or precipitation of gout

NSAIDs, digoxin

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3
Q

Potassium-sparing diuretics

A

Gastrointestinal

NSAIDs, ACE inhibitors

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4
Q

Osmotic diuretics

A

Hypotension

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5
Q

Carbonic anhydrase inhibitors

A

Parasthesia

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6
Q

ACE inhibitors

A

Cough, hyperkalemia

Lithium, NSAIDs

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7
Q

ARBs

A

Hypotension, fatigue

Diuretics

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8
Q

Neprilysin inhibitors

A

Hypokalemia, hypoglycemia

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9
Q

Beta blockers

A

Bradycardia, bronchospasm

NSAIDs, digoxin

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10
Q

Alpha blockers

A

Dizziness, headache

Hypotensive drugs

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11
Q

Calcium channel blockers

A

Ankle swelling, oedema

Beta blockers, digoxin

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12
Q

Nitrates

A

Hypotension, headache

Antihypertensives

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13
Q

Sympathomimetics

A

Arrhythmia

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14
Q

Antiplatelets

A

GI irritation and bleeding

Anticoagulants

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15
Q

Coumarin

A

Abnormal bleeding

NSAIDs, diuretics (multiple drug interactions)

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16
Q

Direct Factor Xa inhibitors

A

Abnormal bleeding

17
Q

Heparins

A

Abnormal bleeding

18
Q

HMG-CoA reductase inhibitors

A

Myalgia

Verapamil, macrolides

19
Q

Class I anti-arrhythmics

A

Oedema

20
Q

Class II anti-arrhythmics

A

Hypotension

21
Q

Class III anti-arrhythmics

A

Nausea and vomiting

22
Q

Class IV anti-arrhythmics

A

Hypotension (verapamil)

Constipation (diltiazem)

23
Q

Cardiac glycosides

A

Fatigue, nausea

24
Q

Adenosine

A

Nausea

Contraindicated in obstructive airway disease

25
Q

Antimuscarinic/anticholinergic

A

Urinary retention

26
Q

Magnesium

A

Electrolyte irregularities

27
Q

Direct renin inhibitor

A

Diarrhoea, cough

28
Q

Alpha-2-adrenergic agonist

A

Constipation, dry mouth

29
Q

Selective I(f) current inhibitors

A

Bradycardia

30
Q

Anticoagulants - direct thrombin inhibitor

A

Abnormal bleeding, bruising

31
Q

Thrombolytics/fibrinolytics

A

Haemorrhage, ecchymosis, hypotension