Respiratory system 2 Flashcards

1
Q

What makes up the Lower Respiratory tract (LRT)

A
Larynx
Trachea
Bronchi
Bronchioles
Alveoli
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2
Q

What is the function of the LRT

A

Conducts air to/from site of gas exchange
Completes cleaning, warming and humidifying of air
Barrier between air and blood (large surface area for gas exchange)

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3
Q

Describe the larynx

A

Air passage
Cartilages protect and maintain open airways
Epiglottis closes over airway when swallowing

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4
Q

Where is the larynx located

A

Anterior to esophagus

From hyoid bone to trachea

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5
Q

What are the main bits of cartilage in the larynx

A

Epiglottis (just under tongue)
Thyroid cartilage (laryngeal prominence)
Cricoid cartilage

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6
Q

What is the glottis

A

Voice box

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7
Q

What are the two types of folds

A

Vocal folds

Vestibular folds

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8
Q

Where are the vocal folds

A

Attached to cartilages

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9
Q

Describe vocal folds

A

‘true’ vocal cords
Passing air causes vibrations (sounds waves)
Used for normal speech

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10
Q

What affects vocal folds

A

Testosterone - affects the cartilage and muscle - Longer, thicker folds. Deeper voice

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11
Q

Describe Vestibular folds

A

‘false’ vocal cords
Superior to vocal cords
Prevent foreign object entry to glottis
Produce deep sounds`

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12
Q

Where is the trachea located

A

Anterior to esophagus

Between larynx and primary bronchi

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13
Q

What are the functions of the trachea

A

Maintain patent airway - C-shaped cartilage rings
- Elastin fibres in lamina propria/submucosa
Clean, warm, humidify air

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14
Q

What connects the ends of C shaped cartilage rings

A

Trachealis - band of smooth muscle - contracts for coughing (as well as elastin fibres recoiling)

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15
Q

How are debris removed from the trachea

A

Mucociliary escalator - goblet cells and mucus glands coat surface and traps debris. Cilia move mucus up to pharynx to be swallowed and digested

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16
Q

How many lobes does each lung have

A

Right has 3

Left has 2

17
Q

What is the hilum

A

Where bronchi and blood vessels enter

18
Q

What is the costal surface of the lungs

A

Outer surface - against ribs

19
Q

Describe 1 degree bronchi

A

Respiratory epithelium

Complete cartilage and smooth muscle rings

20
Q

Describe 2 and 3 degree bronchi

A

Respiratory epithelium decease in height
Num. of goblet cells decrease
Cartilage plates (air P holds open)

21
Q

Describe Bronchioles

A

Cuboidal epithelium
No cartilage
Thick smooth muscle for bronchoconstriction/dilation
No goblet cells

22
Q

Describe Terminal Bronchioles

A

Each supplies a pulmonary lobule

Site of gas exchange

23
Q

What is a pulmonary lobule

A

Made up of many alveoli (air sacks)
Most of lunch volume - enormous surface area
(150 million alveoli per lung)

24
Q

Describe alveoli

A

Very thin - simple squamous epithelium on thin basement membrane
Covered in fine network of pulmonary capillaries
Open at one end

25
Q

What are the two types of pneumocytes

A

(lung epithelial cells)
Type 1 squamous
Type 2 cuboidal

26
Q

Describe Type 1 squamous

A

Forms respiratory membrane (blood-air barrier) with capillary wall and shared basement membrane

27
Q

Describe type 2 cuboidal

A

Scattered amongst type 1

secrete surfactant - complex lipoprotein (phospholipid) - reduces surface tension of alveolar fluid.

28
Q

Describe structure of alveolus

A

Roaming macrophage - removes debris
Capillary (oxygenated blood)
Connections to neighbouring alveoli

29
Q

What are the layers of the respiratory membrane (From air to blood)

A

Alveolar cell layer (type 1 epithelial cell)
Fused basement membrane
Capillary endothelium