Respiratory Drugs Flashcards
Name some EGFR drugs:
Cetuximab
Name EML4 ALK inhibitors:
Crizotinib
Name PDL1 inhibitors:
Nivolumab
What drugs can be used in Idiotpathic pulmonary fibrosis?
Pirfenidine
- stops fibrosis
Nintedanib
- intracellular tyrosine kinase inhibitor
N - Acetly - cysteine
- anti- mucolytic
oxygen therapy
diuretics
antibiotics
Name two anti-cholinergics:
Ipratropium bromide
Oxitriopium bromide
What drugs stop the break down of cAMP in the smooth muscle of the bronchi?
Theophyllines
Name two Leukotriene receptor antagonists:
Montelukast
ZAfirlukast
Name three combination inhalers:
Seretide
Fostair
Symbicort
What are some important side affects of SABA?
tremor
tachycardia
heart arrhythmias
sleep disturbance
What actions does SABA have?
Bronchodilation
increased cilia movement
Reduced pro-inflammatory activation of mast cells
Name two ICS: and their mechanism of action:
Beclomethasone
Fluticasone
- reduced inflammation
- increased B2 upregulation
Name some side effects of ICS:
Oral Candidiasis
Adrenal suppression
Osteoprosis
What type of drug is theophylines?
Methylxanthines
What receptors do Antimuscarinics bind too?
M1 and M3
What are some side effects to antimuscarinics?
Dry mouth
blurred vision
urinary retention
