respiratory

Question 1

antihistamine nomenclature for h1 1st gen

Answer 1

-en/-ine or -en/-ate or -zine (with exception of cetirizine)

Question 2

nomenclautre for antihistamine h1 2nd gen

Answer 2

end in -adine and cetirizine. vs h2 which is -dine

Question 3

1st gen uses

Answer 3

urticaria, motion sickness, sleep aid

Question 4

adverse effects of 1st gen

Answer 4

sedtation, antimuscarinic, anti a adrenergic

(u) caution in elderly with cognitive or fxnal impairment

antimuscarinic action with cross BBB and can cause sedation and decreased cognition

Question 5

second gen uses

Answer 5

urticaria and allergy

Question 6

second gen adverse effects

Answer 6

far less sedating that first because decreased BBB

Question 7

guaifenesin

Answer 7

648

Question 8

n-acetylcysteine

Answer 8

648

Question 9

dextromethorphan mech

Answer 9

648

Question 10

dextromethorphan use

Answer 10

648

Question 11

dextromethorphan analog of?

Answer 11

648

Question 12

dextromethorphan extra effect

Answer 12

648

Question 13

dextromethorphan OD

Answer 13

remember mild abuse potential

Question 14

dextromethorphan can cause?

Answer 14

serotonin syndrome

Question 15

pseudophedrine use

Answer 15

648

Question 16

pseudophedrine mech

Answer 16

648

Question 17

pseudophedrine adverse effects

Answer 17

648

Question 18

bosentan use, mech, side effect

Answer 18

648

Question 19

sildenafil use, mech, side effect

Answer 19

648

Question 20

epoprostenol, iloprost use, mech, side effect

Answer 20

648

Question 21

albuterol use

Answer 21

acute exacerbation of asthma/copd

Question 22

albuterol adverse effects

Answer 22

649

Question 23

salmeterol/ formoterol use

Answer 23

copd/asthma long acting (always with glucocorticoid)

Question 24

salmeterol/ formoterol adverse effects

Answer 24

649

Question 25

fluticasone, budesonide mech and use

Answer 25

649 copd and asthma

Question 26

fluticasone, budesonide adverse effect

Answer 26

649

Question 27

tiotropium/ipratropium use

Answer 27

copd and asthma

Question 28

ipratropium lenght

Answer 28

649

Question 29

tiotropium length

Answer 29

649

Question 30

montelukast, zafirlukast mech and use

Answer 30

649

Question 31

zileuton use and side effect

Answer 31

649

Question 32

omalizumab mech and use

Answer 32

649

Question 33

methylxanthines

Answer 33

theophylline

Question 34

theophylline mechanism

Answer 34

blocks phosphdiestarese and icnreases camp

also looks like adenosine receptor atagonism (this is why adenosine wouldnt break a tachy)

Question 35

theophylline adverse

Answer 35

narrow therapeutic index (cardiotoxic and neurotoxic)

mateabolized by p450

Question 36

theophylline use

Answer 36

asthma and copd

Question 37

theophylline toxicity

Answer 37

(u) mild maybe only cortical arousal and insomnia

more serious nausea, vomiting, tachyarrythmias, seizures and abdominal pain

Question 38

treat theophylline toxicity with

Answer 38

charcoal (reduce absorption)

b blockers for tachy arrythmia

benzos, barbituates, for seizure

Question 39

methacholine

Answer 39

used in the bronchial challenge for diagnosis of asthma