immuno pharm Flashcards by John-Paul Cathcart Jr.

Q

immunosuppresants basics: general action?

A

block lymphocyte activation and proliferation

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Q

immunosuppresants basics: use

A

reduce acute transplant rejection by supressing cellular immunity (used as prophylaxis)

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Q

immunosuppresants basics: why combine?

A

increase efficacy and decrease toxicity

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Q

immunosuppresants basics: increased risk for?

A

infection and malignancy

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Q

cyclosporine mec

A

116

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Q

cyclosporine use

A

116

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Q

cyclosporine toxicity

A

hyperkalemia, hyperglycemia

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Q

tacrolimus (fk506) mech

A

116

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Q

tacrolimus (fk506) toxicity

A

116

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Q

tacrolimus (fk506)

A

116

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Q

cyclosproine and tacrolimus pharmacology

A

cyp p450 metabolism

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Q

sirolimus (rapamycin) mech

A

116

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Q

sirolimus (rapamycin) use

A

116

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Q

sirolimus (rapamycin) toxicity

A

116

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Q

sirolimus (rapamycin) notes

A

116

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Q

basiliximab mech

A

116

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Q

basiliximab use

A

116

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Q

basiliximab effects

A

116

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Q

azathioprine mech

A

116

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Q

azathioprine use

A

116

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Q

azathioprine toxicity

A

116

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Q

azathioprine notes

A

116

Q

mycophenolate mofetil mech

A

116

Q

mycophenolate mofetil use

A

116

mycophenolate mofetil toxicity

116

mycophenolate mofetil notes

116

corticosteroids mech

116116

corticosteroids uses

116

corticosteroids effects

116

corticosteroids notes

116

Aldesleukin

117

epoetin alfa

117

filgrastim

117

sargramostin

117

ifn alpha

117

ifn b

117

ifn g

117

romiplostim

117

eltrombopag

117

oprelvekin

117

alemtuzumab target, clinical use,

118

bevacizumab target, clinical use,

118

cetuximab target, clinical use,

118

rituxumab target, clinical use,

118

trastuzumab target, clinical use, notes

118

daclizumab target, clinical use,

118

eculizumab target, clinical use,

118

natalizumab target, clinical use, notes

118

ustekinumab target, clinical use,

118

abciximab target, clinical use,

118

denosumab target, clinical use,

118

ranibizumab target, clinical use,

118

bevacizumab extra use

118