Respiratory Flashcards
Fluid seen in Cardiogenic Pulmonary edema
Transudate
hemosiderin is contained in residual bodies derived from lysosomes
Telolysosomes
histologic manifestation of Acute lung injury/ARDS
Diffuse alveolar damage
persistent cough with sputum production for at least 2 consecutive years
Smoker
Excessive mucinous/mucopurulent secretions
Goblet cell hyperplasia
Fibrosis of bronchiolar wall
Chronic bronchitis
MCC of ALI
sepsis
Diffuse pulmo infection
Gastric aspiration
head mechanical trauma
MC type of emphysema
RF: smoking
Centriacinar
RF for Pancinar
a-1 antitrypsin deficiency
persistent severe infection
Foul smelling sputum
Hemoptysis
severe persistent cough
Permanent dilation of bronchi and bronchioles
Bronchiectasis
progressive fibrosis
respiratory failure
early lesion: fibroblastic focus
late: HONEY COMB fibrosis
Idiopatic pulmonary fibrosis
polypoid plugs of loose organizing CT within airways and alveoli
Masson bodies
seen in Cryptogenic organizing pneumonia/Bronchiolitis obliterans
MC indication for lung transplantation
IPF > COPD
Most prevalent chronic occupational disease
Silicosis
radiography: fine nodularities upper lobes, eggshell calcification
particulates coated with similar iron protein complexes
Ferruginous bodies (non asbetosis)
charcot-leyden crystal seen in BA is derived from
Galectin-10
Non-caseating granuloma with giant cells that may contain Shaumann bodies and Asteroid bodies
Sarcoidosis
MC involved organ:LN and lungs
laminated concentration composed of Calcium and proteins
Schaumann Bodies
Mean pulmonary artery pressure
> /25 mmHg at rest
MCC of CAP
S. pneumoniae
MC bacterial cause of acute exacerbation of COPD
H. influenzae
Type of pneumonia:
Intra alveolar inflammation
Neutrophilic infiltrate
Bacterial pneumonia
Type of pneumonia:
Interstitial inflammation
Mononulcear infiltrate
Viral Pneumonia
Etiologic agent:
MCC of gram negative bacterial pneumonia
Current jelly sputum
Klebsiella pneumonia
MC site of metastatic neoplasm
Lung metastasis
MC Lung Carcinoma
Adenocarcinoma
tumor cells crawl along normal appearing alveolar septa
Lepidic cells
seen in adenocarcinoma
Small Cell Carcinoma is derived from
Kulchitsky cells
Basophilic staining of vascular walls
Azzopardi effect
seen in Small Cell Ca
Most aggressive among Lung Carcinoma
Small cell carcinoma
Lung Carcinoma situated at Central/Hilar
+ Keratinization, Intercellular bridges
IHC: p40, p63
Squamous Cell Ca
penetration of tumor into PERIBRONCHIAL Tissue
Collar-button lesion
seen in Bronchial Carcinoid Tumor
kulchitsky cells
salt and pepper finely granular chromatin
high mitosis
Azzopardi effect
small cells with scant cytoplasm
nuclear molding
Small Cell Carcinoma
Characteristic of PLeural fluid
15 mL normally serous acellular clear fluid
chest pain
dyspnea
Recurrent pleural effusion
assoc with asbestosis
Malignant mesotheliioma
2 common paraneoplastic syndrome associated with small cell lung cancer
SIADH
Cushing syndrome
4 stages of inflammation seen in lobar pneumonia
Congestion
Red hepatization
Gray Hepatization
Resolution
Enopthlamos, Ptosis, Myosis, anhidrosis
Syndrome? location?
Horner Syndrome
Pancoart Tumor
