GUT

Question 1

MCC of Hydronephrosis in infants and children

Answer 1

Ureteropelvic junction obstruction

Common: male, bilateral, assoc with CL renal agenesis

Question 2

MC primary malignant tumor of Ureter

Answer 2

Urothelial Carcinoma

Question 3

MC and most serious congenital anomaly of the urinary bladder

Answer 3

Vesicourethral reflux – due to predisposition to infection and scarring

Question 4

laminated mineralized concentration in phagolysosome

Answer 4

Michaelis-Gutmann bodies
seen in Malakoplakia

Question 5

MC bladder neoplasm

Answer 5

Urothelial Neoplasm
MC in males and advancing age
Smoking
Painless hematuria

Question 6

MC benign mesenchymal tumor of the UB

Answer 6

Leiomyoma

Question 7

MC sarcoma of the UB in adults

Answer 7

Leiomyosarcoma

Question 8

MC sarcoma of the UB in children

Answer 8

Embryonal Rhabdomyosarcoma/Sarcoma botryoides

Question 9

MCC of UB obstruction in male

Answer 9

nodular prostatic hyperplasia

Question 10

MCC of UB obstruction in female

Answer 10

Cystocele of the bladder

Question 11

Penile Intraepithelial Neoplasia (Non-HPV) associated with

Answer 11

Balanitis xerotica obliterans
+ squamous differntiation

Question 12

MCC of Reiters syndrome

Answer 12

Chlamydia

Question 13

Marker for HPV related Cancer

Answer 13

p16

Question 14

MC location of undescended testis

Answer 14

Inguinal Canal

Question 15

MC phase of arrest in Cryptorchidism

Answer 15

Inguinoscrotal - (4-7 mos AOG)

Question 16

Cause of Orchitis and Epididymitis in sexually active <35 yrs

Answer 16

C. trachomatis
N. gonorrhea

Question 17

Cause of Orchitis and Epididymitis in UTI >35y/o

Answer 17

E coli
Pseudomonas

Question 18

MCC of painless testicular enlargement

Answer 18

Testicular Tumors
Germ Cell 95%

Question 19

MC testicular GCT in infants and children up to 3 yrs

Answer 19

Yolk sac tumors
+ Schiller-Duval (glomerulonoid) bodies
+ AFP
Excellent prognosis

Question 20

20-30s
hemorrhage and necrosis
highly anaplastic
locally aggressive
Lymphovascular invasion
+Cytokeratin

Answer 20

Embryonal Carcinoma

Question 21

MC GCT

Answer 21

Seminoma
4th decade
no hemorrhage and necrosis
lymphocytic infiltrate
+ KIT
favorable

Question 22

MC testicular neoplasm in >60 y/o
MC form

Answer 22

Testicular lymphoma
MC form: DLBCL
aggressive tumor

Question 23

2nd MC testicular tumor in infants and children

Answer 23

Testicular teratoma

Question 24

2nd MC GCT in adults

Answer 24

Mixed GCT

Question 25

MC form of prostatides

Answer 25

Chronic Abacterial prostatitis
WBC >10/HPF
- culture

Question 26

MC site of prostatic adenocarcinoma

Answer 26

Peripheral zone

Question 27

MC benign prostatic dse in men 50 y/o

Answer 27

BPH
site: Transitional zone

Question 28

start of screening of prostate cancer

Answer 28

45 yrs old
DRE and PSA

Question 29

Fever, chills
tender boggy upon DRE
>15/hpf
+ culture

Answer 29

Acute bacterial prostatitis

Question 30

low back pain, dysuria, suprapubic discomfort
+ history of recurrent UTI
>15/hpf
+ culture

Answer 30

Chronic bacterial prostatitis

Question 31

tumor suppressor gene inactivated by the HPV-encoded protein E6? E7?

Answer 31

E6 - p53
E7 - RB