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Pathology > GIT > Flashcards

GIT Flashcards

1
Q

ulcer associated with burns and trauma

A

CuRLing ulcers

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2
Q

ulcers associated with increased ICP due to TBI

A

CuSHings ulcer

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3
Q

MC type of esophageal atresia

A

Type C, distal tracheoesophageal fistula with proximal esophageal atresia

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4
Q

MC form of congenital intestinal atresia

A

imperforate anus - failure of cloacal membrane involution

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5
Q

posterolateral defect of diaphragmatic hernia, left sided

A

Bochdalek - most common

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6
Q

anteromedial defect of diaphragmatic hernia

A

Morgagni

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7
Q

MC congenital anomaly of the GI tract

A

Meckel diverticulum

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8
Q

2 association of Pyloric Stenosis

A

Turner syndrome, Trisomy 18
Erythromycin/Azithromycin exposure in 1st 2 weeks of life

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9
Q

mutation in Hirschsprung disease

A

RET mutations

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10
Q

MC esophageal obstruction

A

Nutcracker esophagus
high amplitude contractions of the distal esophagus

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11
Q

false diverticulum above UES
Cricopharyngeus dysfunction
regurgitation, halitosis

A

Pharyngoesophageal/ Zenker

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12
Q

Plummer Vinson syndrome TRIAD

A

UE webs
IDA
Glossitis, Cheilosis

webs: semi-circumferential ledge-like mucosal protrusions

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13
Q

TRIAD of Achalasia (aganglionic esophagus)

A

Incomplete LES relaxation
Increase LES tone
Esophageal aperistalsis

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14
Q

longitudinal mucosal tear near GEJ
severe retching or vomiting
hematemesis
antipersitaltic contractile wave

A

Mallory Weiss tear

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15
Q

MCC of esophageal varices

A

Liver cirrhosis

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16
Q

hallmark of barrett esophagus

A

Goblet cells

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17
Q

MC Esophageal carcinoma

A

Squamous Cell Carcinoma
site: middle thrid

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18
Q

Precursor lesion of Squamous cell carcinoma

A

Squamous dysplasia

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19
Q

which has an increased acid secretion in PUD

A

Duodenal Ulcer

20
Q

disease characterized by GIANT CEREBRRIFORM enlargement of rugal folds due to epithelial hyperplasia without inflammation

A

Hypertrophic Gastropathies

21
Q

MC gastric polyp

A

Inflammatory/hyperplastic polyp
assoc with H. pylori infection

22
Q

MC malignancy of GI

A

Adenocarcinoma

23
Q

MC site of extranodal lymphomas

A

Stomach

24
Q

MC mesenchymal tumor of the abdomen

A

GI stromal tumor

25
Q

Mutation in WNT signaling
Bulky exophytic masses
Ulcerative infiltrative masses
Glandular structures lined by dysplastic intestinal-type epithelial cellsq

A

Intestinal Gastic Ca

26
Q

loss of function mutation of CDH1
Linitis plastica
Dyscohesive cells
Signet-ring cells

A

Diffuse infiltrative Gastric Ca

27
Q

Thickened stiff wall with flattened rugae (leather bottle appearance)

A

Linitis plastica

28
Q

virulence factor of H.pylori

A

CagA

29
Q

MC GI Lymphoma

A

Extranodal Marginal Zone B cell Lymphoma

30
Q

Only malignancy that can be cured by antibiotics

A

MALT lymphoma
H. pylori eradication

31
Q

Carney TRIAD

A

GIST
Paraganglioma
pulmonary chondroma

32
Q

Cytogenic origin of GIST

A

interstitial cells of Cajal

33
Q

MC site of ishemic bowel disease

A

Colon

34
Q

painful, bloody, small-volume diarrhea

A

Exudative diarrhea
seen in Amebic dysentery

35
Q

most feared long-term complication of UC and CD

A

Colitis associated neoplasia

36
Q

Hallmark of Chrons

A

Noncaseating granulomas

37
Q

AD, site: SI
multiple GI hamartomatous polyp and mucocutaneous hyperpigmentation `

A

Peutz Jeghers polyp

38
Q

factors of malignancy risk for colorectal adenoma

A

Size - >/4cm
architecture - villous
degree of dysplasia - high-grade

39
Q

Amsterdam criteria of Verified Lynch Syndrome

A

3 members (1 should be 1st degree relative)
2 generations
1 diagnosed under 50 y/o

40
Q

MC malignancy of GI tract

A

Colorectal adenoCa

41
Q

gatekeeper of colonic mucosa

A

APC

42
Q

Histologic criterion of AP

A

PMN in muscularis propria

43
Q

IHC for GIST

A

CD117

44
Q

Mucinous tumors of the appendix spread to the peritoneum – causing build-up of semisolid mucin in the abdomen

A

pseudomyxoma peritonei

45
Q

neuroendocrine tumors found in which part of the body tend to be multiple and aggressive

A

midgut - jejunum and ileum

46
Q

MC site foe neuroendocrine tumors

A

SI

Pathology (18 decks)

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