Neoplasm Flashcards
Benign but disorganized
Hamartoma
example of Hamartoma
Peutz Jeghers polyp
Cytologically and achi Normal but located in different site (ectopic)
Choriostoma
example of Choriostoma
Ectopic gastric tissue in Meckel Diverticulum
example of Mixed tumor – epithelial + mesenchymal
Pleomorphic adenoma
hallmark of malignancy
Anaplasia
full thickness dysplasia WITHOUT invasion of the base membrane
carcinoma-in-situ - no differentiationfor staging
primary route of Carcinoma
Lymphatic
Primary route of Sarcoma
hematogenous
4 Carcinoma with Hematogenous route
Follicular Thyroid Ca
ChorioCarcinoma
HCC
RCC
MC incidence of Cancer in Male
Protate Ca > Lung Ca > Colorectal
MC incidence of Cancer in Female
Breast Ca > Lung Ca > Colorectal = Uterus
MC mortality of Cancer in Male
Lung > Prostate > Colorectal
MC mortality of Cancer in Female
Lung Ca > Breast > Colorectal = Pancreas
MC type of abnormality involving proto oncogenes in human tuors
RAS
MC paraneoplastic syndrome
Hypercalcemia
Proto oncogene in Pancreatic, Colon and Lung Ca
KRAS
Proto oncogene in Melanoma, NHL, Papillary Thyroid Ca, Hairy cell leukemia
BRAF
Governor of the ell cycle
RB - Chromosome 13
Guardian of the genome
p53 - chromosome 17
inherited mutation of p53
Li-Fraumeni syndrome
technique that detects cellular products or surface markers in a tissue sample
Immunohistochemistry
most potent eosinophil activating cytokines from TH2 cells
IL-5
Cancer caused by Cadmium
Prostate Ca
Cancer caused by Aflatoxin
HCC
Cancer caused by Nitrate
Colon Ca
Cancer cause by Arsenic
Liver - Angiosarcoma
Skin - SCC
Cancer caused by Nitrosamine
Esophageal and Gastric Ca
too much exposure to ANILINE DYE can lead to
Urothelial / Bladder Carcinoma
protco- oncoge can lead to Neuroblastoma
N-MYC
