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Pathology > Neoplasm > Flashcards

Neoplasm Flashcards

1
Q

Benign but disorganized

A

Hamartoma

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2
Q

example of Hamartoma

A

Peutz Jeghers polyp

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3
Q

Cytologically and achi Normal but located in different site (ectopic)

A

Choriostoma

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4
Q

example of Choriostoma

A

Ectopic gastric tissue in Meckel Diverticulum

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5
Q

example of Mixed tumor – epithelial + mesenchymal

A

Pleomorphic adenoma

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6
Q

hallmark of malignancy

A

Anaplasia

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7
Q

full thickness dysplasia WITHOUT invasion of the base membrane

A

carcinoma-in-situ - no differentiationfor staging

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8
Q

primary route of Carcinoma

A

Lymphatic

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9
Q

Primary route of Sarcoma

A

hematogenous

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10
Q

4 Carcinoma with Hematogenous route

A

Follicular Thyroid Ca
ChorioCarcinoma
HCC
RCC

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11
Q

MC incidence of Cancer in Male

A

Protate Ca > Lung Ca > Colorectal

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12
Q

MC incidence of Cancer in Female

A

Breast Ca > Lung Ca > Colorectal = Uterus

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13
Q

MC mortality of Cancer in Male

A

Lung > Prostate > Colorectal

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14
Q

MC mortality of Cancer in Female

A

Lung Ca > Breast > Colorectal = Pancreas

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15
Q

MC type of abnormality involving proto oncogenes in human tuors

A

RAS

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16
Q

MC paraneoplastic syndrome

A

Hypercalcemia

17
Q

Proto oncogene in Pancreatic, Colon and Lung Ca

A

KRAS

18
Q

Proto oncogene in Melanoma, NHL, Papillary Thyroid Ca, Hairy cell leukemia

A

BRAF

19
Q

Governor of the ell cycle

A

RB - Chromosome 13

20
Q

Guardian of the genome

A

p53 - chromosome 17

21
Q

inherited mutation of p53

A

Li-Fraumeni syndrome

22
Q

technique that detects cellular products or surface markers in a tissue sample

A

Immunohistochemistry

23
Q

most potent eosinophil activating cytokines from TH2 cells

A

IL-5

24
Q

Cancer caused by Cadmium

A

Prostate Ca

25
Q

Cancer caused by Aflatoxin

A

HCC

26
Q

Cancer caused by Nitrate

A

Colon Ca

27
Q

Cancer cause by Arsenic

A

Liver - Angiosarcoma
Skin - SCC

28
Q

Cancer caused by Nitrosamine

A

Esophageal and Gastric Ca

29
Q

too much exposure to ANILINE DYE can lead to

A

Urothelial / Bladder Carcinoma

30
Q

protco- oncoge can lead to Neuroblastoma

A

N-MYC

Pathology (18 decks)

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