Reproduction Flashcards

1
Q

Ovarian tumor w/ fallopian tube-like epithelial lining

A

Serous Cystadenoma

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2
Q

Ovarian tumor w/ ascites & hydrothorax

A

Ovarian Fibroma

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3
Q

Ovarian tumor w/ different tissue types

A

Teratoma

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4
Q

Ovarian tumor w/ elevated b-hCG

A

Choriocarcinoma

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5
Q

Ovarian tumor resembling bladder epithelium

A

Brenner Tumor

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6
Q

Meigs Syndrome

A

Ovarian Fibroma + ascites + hydrothorax

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7
Q

Ovarian tumor secreting estrogen -> precocious puberty

A

Granulosa-Theca Cell Tumor

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8
Q

Ovarian tumor producing AFP

A

Yolk Sac Tumor (Endodermal Sinus Tumor)

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9
Q

Ovarian tumor w/ Psammoma Bodies

A

Serous Cystadenocarcinoma

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10
Q

Ovarian tumor w/ intraperitoneal accumulation of mutinous material

A

Mucinous Epithelial Cystadenocarcinoma

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11
Q

Ovarian tumor secreting Testosterone -> virilization

A

Sertoli-Leydig Cell Tumor

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12
Q

Drug given to inhibit Prolactin secretion?

A

Bromocriptine (DA analog)

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13
Q

2-cell theory of Estradiol production

A

LH -> Theca Cells -> Desmolase
(Cholesterol —> Androstenedione)
FSH -> Granulosa Cells -> Aromatase (Androstenedione —> Estrogen)

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14
Q

Testicular Tumor - “fried egg appearance”

A

Seminoma

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15
Q

Testicular Tumor - alveolar or tubular appearance w/ papillary convolutions

A

Embryonal Carcinoma

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16
Q

Testicular Tumor - Schiller-Duval bodies

A

Yolk Sac tumor

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17
Q

Testicular Tumor - high AFP

A

Yolk Sac tumor

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18
Q

Testicular Tumor - high b-hCG

A

Choriocarcinoma

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19
Q

Testicular Tumor - composed of syncytiotrophoblasts & cytotrophoblasts

A

Choriocarcinoma

20
Q

Testicular Tumor - multiple tissue types

A

Teratoma

21
Q

Testicular Tumor - Reinke crystals

A

Leydig cell tumor

22
Q

Testicular Tumor - Androgen producing -> precocious puberty, gynecomastia

A

Leydig cell tumor

23
Q

Testicular Tumor - Estrogen secretion

A

Sertoli cell tumor

24
Q

Most common Testicular Tumor in men >60yo

A

Testicular Lymphoma

25
Q

Most common Testicular Tumor in men >60yo

A

Testicular Lymphoma

26
Q

Testicular tumor composed of cytotrophoblast & syncytiotrophoblasts

A

Choriocarcinoma

27
Q

Testicular tumor that may present initially w/ gynecomastia

A

Leydig cell tumor or Sertoli Cell Tumor

28
Q

Testicular tumor w/ elevated AFP

A

Yolk Sac Tumor

29
Q

Testicular tumor w/ elevated b-hCG

A

Choriocarcinoma or Embryonal Carcinoma

30
Q

Testicular tumor w/ histologic appearance of cytoplasmic clearing “fried egg”

A

Seminoma

31
Q

Deficient Adenosine Deaminase ->

A

SCID

32
Q

Deficient HGPRT ->

A

Lesch-Nyhan Syndrome

33
Q

Most common cause of bloody or serous nipple discharge

A

Intraductal papilloma (benign)

34
Q

RLS of Glycolysis

A

PFK-1

35
Q

RLS of Gluconeogensis

A

Fructose-1,6-bisphosphatase

36
Q

RLS of TCA cycle

A

Isocitrate dehydrogenase

37
Q

RLS of glycogenolysis

A

Glycogen phosphorylase

38
Q

HMP shunt RLS

A

G6PD

39
Q

RLS of fatty acid synthesis

A

acetyl-CoA carboxylase

40
Q

RLS of fatty acid oxidation

A

Carnitine acyltransferase I

41
Q

Ketogenesis RLS

A

HMG-CoA synthase

42
Q

Cholesterol synthesis RLS

A

HMG-CoA reductase

43
Q

Orotic aciduria - deficiency of

A

UMP Synthase (pyrimidine synthesis)

44
Q

Trimethoprim MOA

A

inhibits dihydrofolate reductase

45
Q

Methotrexate MOA

A

inhibits dihydrofolate reductase

46
Q

Hydroxyurea MOA

A

inhibits ribonucleotide reductase