Reproduction Flashcards
Ovarian tumor w/ fallopian tube-like epithelial lining
Serous Cystadenoma
Ovarian tumor w/ ascites & hydrothorax
Ovarian Fibroma
Ovarian tumor w/ different tissue types
Teratoma
Ovarian tumor w/ elevated b-hCG
Choriocarcinoma
Ovarian tumor resembling bladder epithelium
Brenner Tumor
Meigs Syndrome
Ovarian Fibroma + ascites + hydrothorax
Ovarian tumor secreting estrogen -> precocious puberty
Granulosa-Theca Cell Tumor
Ovarian tumor producing AFP
Yolk Sac Tumor (Endodermal Sinus Tumor)
Ovarian tumor w/ Psammoma Bodies
Serous Cystadenocarcinoma
Ovarian tumor w/ intraperitoneal accumulation of mutinous material
Mucinous Epithelial Cystadenocarcinoma
Ovarian tumor secreting Testosterone -> virilization
Sertoli-Leydig Cell Tumor
Drug given to inhibit Prolactin secretion?
Bromocriptine (DA analog)
2-cell theory of Estradiol production
LH -> Theca Cells -> Desmolase
(Cholesterol —> Androstenedione)
FSH -> Granulosa Cells -> Aromatase (Androstenedione —> Estrogen)
Testicular Tumor - “fried egg appearance”
Seminoma
Testicular Tumor - alveolar or tubular appearance w/ papillary convolutions
Embryonal Carcinoma
Testicular Tumor - Schiller-Duval bodies
Yolk Sac tumor
Testicular Tumor - high AFP
Yolk Sac tumor
Testicular Tumor - high b-hCG
Choriocarcinoma
Testicular Tumor - composed of syncytiotrophoblasts & cytotrophoblasts
Choriocarcinoma
Testicular Tumor - multiple tissue types
Teratoma
Testicular Tumor - Reinke crystals
Leydig cell tumor
Testicular Tumor - Androgen producing -> precocious puberty, gynecomastia
Leydig cell tumor
Testicular Tumor - Estrogen secretion
Sertoli cell tumor
Most common Testicular Tumor in men >60yo
Testicular Lymphoma
Most common Testicular Tumor in men >60yo
Testicular Lymphoma
Testicular tumor composed of cytotrophoblast & syncytiotrophoblasts
Choriocarcinoma
Testicular tumor that may present initially w/ gynecomastia
Leydig cell tumor or Sertoli Cell Tumor
Testicular tumor w/ elevated AFP
Yolk Sac Tumor
Testicular tumor w/ elevated b-hCG
Choriocarcinoma or Embryonal Carcinoma
Testicular tumor w/ histologic appearance of cytoplasmic clearing “fried egg”
Seminoma
Deficient Adenosine Deaminase ->
SCID
Deficient HGPRT ->
Lesch-Nyhan Syndrome
Most common cause of bloody or serous nipple discharge
Intraductal papilloma (benign)
RLS of Glycolysis
PFK-1
RLS of Gluconeogensis
Fructose-1,6-bisphosphatase
RLS of TCA cycle
Isocitrate dehydrogenase
RLS of glycogenolysis
Glycogen phosphorylase
HMP shunt RLS
G6PD
RLS of fatty acid synthesis
acetyl-CoA carboxylase
RLS of fatty acid oxidation
Carnitine acyltransferase I
Ketogenesis RLS
HMG-CoA synthase
Cholesterol synthesis RLS
HMG-CoA reductase
Orotic aciduria - deficiency of
UMP Synthase (pyrimidine synthesis)
Trimethoprim MOA
inhibits dihydrofolate reductase
Methotrexate MOA
inhibits dihydrofolate reductase
Hydroxyurea MOA
inhibits ribonucleotide reductase