Reproduction

Question 1

Ovarian tumor w/ fallopian tube-like epithelial lining

Answer 1

Serous Cystadenoma

Question 2

Ovarian tumor w/ ascites & hydrothorax

Answer 2

Ovarian Fibroma

Question 3

Ovarian tumor w/ different tissue types

Answer 3

Teratoma

Question 4

Ovarian tumor w/ elevated b-hCG

Answer 4

Choriocarcinoma

Question 5

Ovarian tumor resembling bladder epithelium

Answer 5

Brenner Tumor

Question 6

Meigs Syndrome

Answer 6

Ovarian Fibroma + ascites + hydrothorax

Question 7

Ovarian tumor secreting estrogen -> precocious puberty

Answer 7

Granulosa-Theca Cell Tumor

Question 8

Ovarian tumor producing AFP

Answer 8

Yolk Sac Tumor (Endodermal Sinus Tumor)

Question 9

Ovarian tumor w/ Psammoma Bodies

Answer 9

Serous Cystadenocarcinoma

Question 10

Ovarian tumor w/ intraperitoneal accumulation of mutinous material

Answer 10

Mucinous Epithelial Cystadenocarcinoma

Question 11

Ovarian tumor secreting Testosterone -> virilization

Answer 11

Sertoli-Leydig Cell Tumor

Question 12

Drug given to inhibit Prolactin secretion?

Answer 12

Bromocriptine (DA analog)

Question 13

2-cell theory of Estradiol production

Answer 13

LH -> Theca Cells -> Desmolase
(Cholesterol —> Androstenedione)
FSH -> Granulosa Cells -> Aromatase (Androstenedione —> Estrogen)

Question 14

Testicular Tumor - “fried egg appearance”

Answer 14

Seminoma

Question 15

Testicular Tumor - alveolar or tubular appearance w/ papillary convolutions

Answer 15

Embryonal Carcinoma

Question 16

Testicular Tumor - Schiller-Duval bodies

Answer 16

Yolk Sac tumor

Question 17

Testicular Tumor - high AFP

Answer 17

Yolk Sac tumor

Question 18

Testicular Tumor - high b-hCG

Answer 18

Choriocarcinoma

Question 19

Testicular Tumor - composed of syncytiotrophoblasts & cytotrophoblasts

Answer 19

Choriocarcinoma

Question 20

Testicular Tumor - multiple tissue types

Answer 20

Teratoma

Question 21

Testicular Tumor - Reinke crystals

Answer 21

Leydig cell tumor

Question 22

Testicular Tumor - Androgen producing -> precocious puberty, gynecomastia

Answer 22

Leydig cell tumor

Question 23

Testicular Tumor - Estrogen secretion

Answer 23

Sertoli cell tumor

Question 24

Most common Testicular Tumor in men >60yo

Answer 24

Testicular Lymphoma

Question 25

Most common Testicular Tumor in men >60yo

Answer 25

Testicular Lymphoma

Question 26

Testicular tumor composed of cytotrophoblast & syncytiotrophoblasts

Answer 26

Choriocarcinoma

Question 27

Testicular tumor that may present initially w/ gynecomastia

Answer 27

Leydig cell tumor or Sertoli Cell Tumor

Question 28

Testicular tumor w/ elevated AFP

Answer 28

Yolk Sac Tumor

Question 29

Testicular tumor w/ elevated b-hCG

Answer 29

Choriocarcinoma or Embryonal Carcinoma

Question 30

Testicular tumor w/ histologic appearance of cytoplasmic clearing "fried egg"

Answer 30

Seminoma

Question 31

Deficient Adenosine Deaminase ->

Answer 31

SCID

Question 32

Deficient HGPRT ->

Answer 32

Lesch-Nyhan Syndrome

Question 33

Most common cause of bloody or serous nipple discharge

Answer 33

Intraductal papilloma (benign)

Question 34

RLS of Glycolysis

Answer 34

PFK-1

Question 35

RLS of Gluconeogensis

Answer 35

Fructose-1,6-bisphosphatase

Question 36

RLS of TCA cycle

Answer 36

Isocitrate dehydrogenase

Question 37

RLS of glycogenolysis

Answer 37

Glycogen phosphorylase

Question 38

HMP shunt RLS

Answer 38

G6PD

Question 39

RLS of fatty acid synthesis

Answer 39

acetyl-CoA carboxylase

Question 40

RLS of fatty acid oxidation

Answer 40

Carnitine acyltransferase I

Question 41

Ketogenesis RLS

Answer 41

HMG-CoA synthase

Question 42

Cholesterol synthesis RLS

Answer 42

HMG-CoA reductase

Question 43

Orotic aciduria - deficiency of

Answer 43

UMP Synthase (pyrimidine synthesis)

Question 44

Trimethoprim MOA

Answer 44

inhibits dihydrofolate reductase

Question 45

Methotrexate MOA

Answer 45

inhibits dihydrofolate reductase

Question 46

Hydroxyurea MOA

Answer 46

inhibits ribonucleotide reductase