Renal Flashcards
“wire loop” appearance on LM
Lupus
Crescentic formation in glomeruli
Rapidly progressive glomerulonephritis
Anti-GBM Ab, hematuria, hemoptysis
Goodpastures
Linear pattern if IgG deposition on IF
Goodpastures
Lumpy-bumpy deposits of IgG, IgM, C3
Poststreptococcal glomerulonephritis
Deposits of IgA in mesangium
IgA nephropathy
Goodpastures is a type ______ HSN
type II HSN
Glomerulonephritis w/ + c-ANCA
Granulomatosis w/ polyangiitis
thinning/splitting of the glomerular basement membrane
Alport Syndrome
Proteinuria > 3.5g/d, thickened BM, BM spikes, subepithelial domes
Membranous Nephropathy
“Tram track” BM, sub endothelial humps + mesangial proliferation
Membranoproliferative glomerulonephritis
Most common nephrotic syndrome in children
Minimal Change disease
Most common nephrotic syndrome in adults
Focal Segmental Glomerulosclerosis
Nephrotic syndrome assoc. w/ HIV pts
Focal Segmental Glomerulosclerosis
Nephrotic syndrome assoc. w/ Hepatitis B or C, Lupus, & Subacute bacterial endocarditis
Membranoproliferative glomerulonephritis
Kimmelstiel-Wilson nodules
Diabetic nephropathy
Flattening or effacement of podocyte foot processes
Minimal Change disease
Subepithelial humps + low C3
Post-streptococcal glomerulonephritis
+ anti-DNaseB titers + nephritis
Post-streptococcal glomerulonephritis
+ASO tites + nephritis
Post-streptococcal glomerulonephritis
Mesangial deposits of IgA, Henoch-Schonlein purpura
IgA nephropathy (Berger Disease)
Nephritis, deafness, blindnes
Alport Syndrome
Protein deposits in heart, kidney, lung, assoc w/ Multiple Myeloma
Amyloidosis
Diffuse proliferative nephritis, wire-loop BM
Lupus nephritis
Type II HSN, pulmonary infiltrates, anti-GBM Ab
Goodpastures
Nasopharyngeal granulomas, pulmonary infiltrates, nephritis
Granulomatosis w/ polyangiitis
Responds to corticosteroids
Minimal Change disease
Subendothelial humps & “tram-track” appearance
Membranoproliferative Glomerulonephritis
Segmental sclerosis
Focal Segmental Glomerulosclerosis
purpura on arms, legs, and pain , IgA Nephropathy
Henoch-Schonlein purpura
Apple-green birefringence w/ Congo Red stain
Amyloidosis
Spiking of the GBM d/t sub epithelial deposits
Membranous Nephropathy