Charts & Memorization Flashcards
IL-1
fever
IL-2
T-cell proliferation, differentiation, & activation
IL-3
Stimulation of bone marrow stem cell growth & differentiation
IL-4
Stimulates B-cells, increased IgE, IgG (Th0 –>Th2)
IL-5
IgA, Eosinophil stimulation
IL-6
fever, acute phase protein
IL-10
Inhibits Th1 & macrophages
IL-8
Neutrophil Chemotaxis
IL-12
Tho –>Th1
IFN-alpha
decreased protein synth., activation of ribonuclease, prevents neighboring cells from viral inf.
IFN-beta
decreased protein synth., activation of ribonuclease, prevents neighboring cells from viral inf.
IFN-gamma
Activates macrophages, inhibits production of Th2
Th1 cytokine production
IL-2, IL-3, IFN-gamma
Th2 cytokine production
IL-2, IL-3, IL-4, IL-5, IL-10
Neutrophil Chemotaxis
IL-8, C5a, Leukotriene B4
Cytokines that mediate inflammation
IL-1, IL-6, TNF-alpha
Cytokines released by virus-infected cells
IFN-alpha, IFN-beta
Anti-IgG Ab
Rheumatoid Arthritis (non-specific)
Anti-citrullinated protein Ab (ACPA)
Rheumatoid Arthritis
Anti-nuclear Ab (ANA)
SLE (non-specific)
Anti-Smith Ab
SLE
Anti-dsDNA Ab
SLE
Anti-histone Ab
Drug-Induced Lupus
Anti-centromere Ab
CREST Scleroderma
Anti-Jo-1 Ab
Polymyositis
Anti-SSA (anti-Ro) Ab
Sjogrens Syndrome
Anti-SSB (anti-La) Ab
Sjogrens Syndrome
Anti-U1-RNP
Mixed CT Disease
Anti-desmoglein
Pemphigus vulgaris
Anti-ACh receptor
Myasthenia Gravis
Anti-endomysial (anti-tissue transglutaminase)
Celiac Ds
Anti-gliadin
Celiac Ds
Anti-mitochondrial Ab
Primary Biliary Cirrhosis
Anti-smooth mm. Ab
Autoimmune Hepatitis
Anti-glutamate decarboxylase Ab
DM Type I
Anti-thyrotropin Ab
Graves Ds
Anti-throid peroxidase Ab
Hashimoto Thyroiditis
Anti-thyroglobulin Ab
Hashimoto Thyroiditis or Graves Ds
Anti-basement membrane Ab
Goodpasture’s Disease
c-ANCA
Granulomatosis w/ polyangiitis
p-ANCA
Pauci-immune crescentic GN
Churg-Strauss
Microscopic Polyangiitis
Vimentin stains
Connective tissue
Desmin stains
Muscle
Cytokeratin stains
Epithelial cells
GFAP stains
Neuroglia
Neurofilaments stain
neurons