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DIT > Charts & Memorization > Flashcards

Charts & Memorization Flashcards

1
Q

IL-1

A

fever

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2
Q

IL-2

A

T-cell proliferation, differentiation, & activation

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3
Q

IL-3

A

Stimulation of bone marrow stem cell growth & differentiation

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4
Q

IL-4

A

Stimulates B-cells, increased IgE, IgG (Th0 –>Th2)

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5
Q

IL-5

A

IgA, Eosinophil stimulation

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6
Q

IL-6

A

fever, acute phase protein

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7
Q

IL-10

A

Inhibits Th1 & macrophages

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8
Q

IL-8

A

Neutrophil Chemotaxis

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9
Q

IL-12

A

Tho –>Th1

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10
Q

IFN-alpha

A

decreased protein synth., activation of ribonuclease, prevents neighboring cells from viral inf.

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11
Q

IFN-beta

A

decreased protein synth., activation of ribonuclease, prevents neighboring cells from viral inf.

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12
Q

IFN-gamma

A

Activates macrophages, inhibits production of Th2

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13
Q

Th1 cytokine production

A

IL-2, IL-3, IFN-gamma

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14
Q

Th2 cytokine production

A

IL-2, IL-3, IL-4, IL-5, IL-10

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15
Q

Neutrophil Chemotaxis

A

IL-8, C5a, Leukotriene B4

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16
Q

Cytokines that mediate inflammation

A

IL-1, IL-6, TNF-alpha

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17
Q

Cytokines released by virus-infected cells

A

IFN-alpha, IFN-beta

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18
Q

Anti-IgG Ab

A

Rheumatoid Arthritis (non-specific)

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19
Q

Anti-citrullinated protein Ab (ACPA)

A

Rheumatoid Arthritis

20
Q

Anti-nuclear Ab (ANA)

A

SLE (non-specific)

21
Q

Anti-Smith Ab

22
Q

Anti-dsDNA Ab

23
Q

Anti-histone Ab

A

Drug-Induced Lupus

24
Q

Anti-centromere Ab

A

CREST Scleroderma

25
Q

Anti-Jo-1 Ab

A

Polymyositis

26
Q

Anti-SSA (anti-Ro) Ab

A

Sjogrens Syndrome

27
Q

Anti-SSB (anti-La) Ab

A

Sjogrens Syndrome

28
Q

Anti-U1-RNP

A

Mixed CT Disease

29
Q

Anti-desmoglein

A

Pemphigus vulgaris

30
Q

Anti-ACh receptor

A

Myasthenia Gravis

31
Q

Anti-endomysial (anti-tissue transglutaminase)

32
Q

Anti-gliadin

33
Q

Anti-mitochondrial Ab

A

Primary Biliary Cirrhosis

34
Q

Anti-smooth mm. Ab

A

Autoimmune Hepatitis

35
Q

Anti-glutamate decarboxylase Ab

36
Q

Anti-thyrotropin Ab

37
Q

Anti-throid peroxidase Ab

A

Hashimoto Thyroiditis

38
Q

Anti-thyroglobulin Ab

A

Hashimoto Thyroiditis or Graves Ds

39
Q

Anti-basement membrane Ab

A

Goodpasture’s Disease

40
Q

c-ANCA

A

Granulomatosis w/ polyangiitis

41
Q

p-ANCA

A

Pauci-immune crescentic GN
Churg-Strauss
Microscopic Polyangiitis

42
Q

Vimentin stains

A

Connective tissue

43
Q

Desmin stains

44
Q

Cytokeratin stains

A

Epithelial cells

45
Q

GFAP stains

46
Q

Neurofilaments stain

DIT (22 decks)

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