Charts & Memorization Flashcards
IL-1
fever
IL-2
T-cell proliferation, differentiation, & activation
IL-3
Stimulation of bone marrow stem cell growth & differentiation
IL-4
Stimulates B-cells, increased IgE, IgG (Th0 –>Th2)
IL-5
IgA, Eosinophil stimulation
IL-6
fever, acute phase protein
IL-10
Inhibits Th1 & macrophages
IL-8
Neutrophil Chemotaxis
IL-12
Tho –>Th1
IFN-alpha
decreased protein synth., activation of ribonuclease, prevents neighboring cells from viral inf.
IFN-beta
decreased protein synth., activation of ribonuclease, prevents neighboring cells from viral inf.
IFN-gamma
Activates macrophages, inhibits production of Th2
Th1 cytokine production
IL-2, IL-3, IFN-gamma
Th2 cytokine production
IL-2, IL-3, IL-4, IL-5, IL-10
Neutrophil Chemotaxis
IL-8, C5a, Leukotriene B4
Cytokines that mediate inflammation
IL-1, IL-6, TNF-alpha
Cytokines released by virus-infected cells
IFN-alpha, IFN-beta
Anti-IgG Ab
Rheumatoid Arthritis (non-specific)
Anti-citrullinated protein Ab (ACPA)
Rheumatoid Arthritis
Anti-nuclear Ab (ANA)
SLE (non-specific)
Anti-Smith Ab
SLE
Anti-dsDNA Ab
SLE
Anti-histone Ab
Drug-Induced Lupus
Anti-centromere Ab
CREST Scleroderma
