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pharm II > Repro drugs > Flashcards

Repro drugs Flashcards

1
Q

OvSynch protocol in cattle?

A
  1. Give GNRH
  2. Wait 7 days
  3. Give PG (prostaglandin)
  4. Wait 2 days
  5. Give GNRH again
  6. Wait 24 hrs
  7. Do AI
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2
Q

Which drug is used for superovulation in horses?

A

eCG - equine chorionic gonadotropin

**mixed LH and FSH activity, FSH predominates

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3
Q

Which drug is used for superovulation in cattle?

A

FSH

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4
Q

Which drug is used to prevent ovulation?

A
  1. progesterone
    -prevents LH surge
  2. PRID (progesterone releasing vaginal device) in cattle
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5
Q

Main use of megestrol acetate?

A

Used to prevent or postpone estrus in dogs

  • also used to tx prostatic hyperplasia (dec. LH = dec. testosterone)
  • Skin conditions in cats
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6
Q

Side effects of megestrol acetate use in dogs?

A

Cystic endometrial hyperplasia - pyometra

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7
Q

Main use of mibolerone?

A

Active androgen used to prevent estrus in dogs

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8
Q

Side effects of mibolerone use on female dogs?

A

Female fetuses become masculinized

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9
Q

Dopamine affect on reproduction?

A

Dopamine agonist Inhibits GNRH and prolactin

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10
Q

What drug is used to increase GNRH and advance reproductive season in horses?

A

Domperidone (Dopamine antag)

Sulpiride

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11
Q

Main use and MOA of cabergoline?

A

Dopamine agonist

  • used to terminate pregnancy in dogs (ideally < 25 days)
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12
Q

Main use of altrenogest in horses?

A

Suppress signs of estrus, used to support pregnancy

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13
Q

Which drug is used to induce estrus in pigs?

A

GNRH

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14
Q

Which drug is used to synchronize estrus in pigs?

A

Altrenogest

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15
Q

Main use of estrogen during repro?

A

Supports pregnancy in horses

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16
Q

Drugs used to induce parturition in horses?

A

Oxytocin

17
Q

Drug used to induce parturition in cows and sheep?

A

Corticosteroids

18
Q

Drug used to induce parturition in goats and pigs?

A

PGF2a

19
Q

Drug used to inhibit lactation in dogs in false pregnancy?

A

Cabergoline (Dopamine agonist)

20
Q

Drug used to induce lactation?

A

Domperidone (dopamine antagonist)

21
Q

Main use and MOA of finasteride?

A

5-alpha reductase inhibitor

Prevents conversion of testosterone

  • Tx of benign prostatic hyperplasia
22
Q

Main use and MOA of flutamide?

A

Blocks dihydrotestosterone receptors

  • Used to tx benign prostatic hyperplasia
23
Q

Side effects of prostaglandins when used to inhibit luteolysis?

A
  • none in cattle
  • Sweating and colic in horses
  • Vascular ischemia in dogs
24
Q

Main use of hCG?

A

LH activity!

used to induce ovulation

25
Q

Drug used to induce ovulation in fish?

A

GNRH

26
Q

GNRH is used to induce estrus in which species?

A

Dogs and pigs

27
Q

GNRH is used to induce ovulation in which species?

A

Cattle, horses, fish

28
Q
A

pharm II (23 decks)

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