Renal tubular acidosis (RTA) Flashcards

1
Q

Type 1 (distal)

A

defect in collecting duct’s ability to excrete H+;
untreated pts have urine pH >5.5.

Associated with hypokalemia
Increased risk for calcium phosphate kidney stone
as a result of increased urine pH and bone reabsorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Type 2 (proximal)

A

Defect in proximal tubule bicarb reabsorption;
May be seen with Fanconi’s syndrome
Untreated pts typically have urine pH <5.5

Associated with hypokalemia

Increased risk for hypophosphatemic rickets.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Type 4 (hyperkalemic)

A

Hypoaldo or lack of collecting tubule response to aldo

The resulting hyperkalemia impairs amminogenesis in the proximal tubule, leading to decreased buffering capacity and decreased urine pH.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly