Juxtaglomerular apparatus Flashcards

1
Q

What does it consist of?

A

JG cells: modified smooth muscle of afferent arteriole

Macula dense: NaCl sensor, part of distal convoluted tubule

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2
Q

JG cells function

A

Secretes renin

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3
Q

When is renin secreted?

A

By JG cells when

1) low renal blood pressure
2) low NaCl delivery to distal tubule
3) increased sympathetic tone (beta1)

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4
Q

JGA defends

A

JGA defends glomerular filtration rate via

renin-angiotensin-aldo system

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5
Q

Beta blockers at JGA

A

Beta blockers can decrease BP by inhibiting B1 receptor on the JGA, causes decrease in renin release

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