Juxtaglomerular apparatus Flashcards
1
Q
What does it consist of?
A
JG cells: modified smooth muscle of afferent arteriole
Macula dense: NaCl sensor, part of distal convoluted tubule
2
Q
JG cells function
A
Secretes renin
3
Q
When is renin secreted?
A
By JG cells when
1) low renal blood pressure
2) low NaCl delivery to distal tubule
3) increased sympathetic tone (beta1)
4
Q
JGA defends
A
JGA defends glomerular filtration rate via
renin-angiotensin-aldo system
5
Q
Beta blockers at JGA
A
Beta blockers can decrease BP by inhibiting B1 receptor on the JGA, causes decrease in renin release