Reboxetine (Edronax)

Question 1

Class

Answer 1

selective reuptake inhibitor of noradrenaline

mild inhibitor of serotonin uptake

Question 2

Indications

Answer 2

Major depression

Question 3

Dose Range

Answer 3

4 mg twice daily (m=12 mg/d)

Question 4

Counseling/SE

Answer 4

• Be careful driving or operating machinery until you know how reboxetine affects you.
• You may feel dizzy on standing when taking this medicine. Get up gradually from sitting or lying to minimise this effect; sit or lie down if you become dizzy.
• Tell your doctor if you have difficulty urinating.
• tell the dr if you have any thoughts of harming yourself

SE –> think SSRI

• sweating
• tachycardia
• dry mouth, constipation, urinary retention
• hypotension/hypertension
• impotence, reduced libido
• dizziness headache
• insomnia

Question 5

Monitoring

Answer 5

• psych review (compliance, tolerability and worsening of condition)
• behaviour (increase suicidal thoughts)