mianserin (Lumin)

Question 1

Class

Answer 1

Tetracyclic antidepressant

Question 2

Indications

Answer 2

Major depression

Question 3

Dose Range

Answer 3

60 – 90 mg daily (max. 120mg)

Question 4

Counseling/SE

Answer 4

• This medicine may cause drowsiness or dizziness and may increase the effects of alcohol; do not drive or operate machinery if you are affected.
• Do not stop taking this medicine suddenly unless your doctor tells you to.
• if fever, sore throat or other signs of infection occur seek medical advice
• let the dr know if you have any thoughts of harming yourself

SE –> Similar properties to TCA (less anticholinergic and CV and more sedation)

• dry mouth
• sedation + +
• dizziness
• orthostatic hypotension
• NEUTROPENIA
• seizures

Question 5

Monitoring

Answer 5

• psych review (compliance, tolerability and worsening of condition)
• behaviour (increase in suicidal thoughts)
• blood count