Metronidazole (Flagyl)

Question 1

Class

Answer 1

Nitromidazoles

Question 2

Indications

Answer 2

• Anaerobic bacterial infections
• Protozoal infections
• Dental infection
• Aspiration pneumonia
• Bacterial vaginosis
• H. pylori eradication
• Wounds (e.g. diabetic foot ulcer)

Question 3

Dose Range

Answer 3

200mg-4g daily

Question 4

Counseling/SE

Answer 4

• Take with food
• Avoid alcohol to prevent nausea, vomiting, flushing, headache and palpitations
• Stop and tell dr if you have any numbness, tingling, pain or weakness in hands or feet.
• Dizziness

SE:

• n/v
• abdominal pain
• diarrhoea
• anorexia
• metallic taste, furry tongue
• CNS effects (dizziness, headaches)
• peripheral neuropathy
• disulfuram reaction when taken with alcohol

Question 5

Monitoring

Answer 5

• compliance

- signs of disulfuram reaction