Dipyridamole (Persantin/Asasantin SR)

Question 1

Class

Answer 1

Phosphodiesterase inhibitor

Question 2

Indication

Answer 2

Prevention of thromboembolism in patients with prosthetic heart valves (with warfarin)

Secondary prevention of ischaemic stroke and TIA (including combination with aspirin)

Question 3

Dose Range

Answer 3

300 – 600 mg dailyu in 3 or 4 doses (thromboembolism)

200 mg CR twice daily ( ischaemic stroke and TIA)

Question 4

Counselling/SE

Answer 4

• This medicine is absorbed best if taken on an empty stomach 1 hour before, or 2 hours after, meals. If it upsets your stomach, it can be taken with food or milk.
• tell dr if you experience bad headache

SE:

• GI upset (n, v, d)
• headache
• hot flushes
• hypotension

Question 5

Monitoring

Answer 5

• cardiovascular function

- compliance