bupropion (Zyban) Flashcards
Class
dopamine and noradrenaline reuptake inhibitor
Indications
Smoking cessation
Dose Range
initially, 150 mg once daily in the morning for 3 days, then 150 mg twice daily (doses at least 8 hours apart) for 7–9 weeks
Counselling/SE
- swallow tablets whole (do not crush, cut or chew).
- Start taking this medicine for at least a week before you stop smoking because it takes this long for it to become effective. It is best if you start by taking it in the morning for the first few days to minimise sleep disturbance.
- If you develop a rash, swelling of the lips or mouth, or difficulty in breathing, contact your doctor immediately and stop taking bupropion.
- Stop taking bupropion and tell your doctor if you are agitated, depressed, have suicidal thoughts or find that you are behaving differently.
- Drink only small quantities of alcohol when you are taking this medicine, as it can increase the risk of fits and other unpleasant effects.
- This medication may have side effects (like dizziness and difficulty in concentrating), which could affect your ability to drive and operate machinery; avoid these activities until you know how bupropion affects you.
Smoking cessation counselling:
- contact support services such as Quitline for extra support and tips
- avoid situations which were previously associated with having a cigarette
- carry a pen or gum for hand-to- mouth movement
- carry small snacks
- regular exercise and may help you quit and also avoid putting on weight smokers who plan before they quit
and set a date are more successful when you get the urge - - remember the 4 D’s; so something else, delay, deep breathe, drink water
- if you have a cigarette it is not the end of your quit attempt but rather a setback
SE: THINK SSRI
- dry mouth,
- constipation
- dizziness
- concentration difficulties
- insomnia
- nightmares
- agitation anxiety tremor
- fever rash
- seizures
- anorexia
Monitoring
Compliance
Psych review
Weight
