Random Stuff 4 Flashcards
Which abx are only effective against aerobic organisms?
Aminoglycoside (mycins)
What are the four most common locations for ectopic pregnancies, in order?
- Ampulla
- Isthmus
- Fimbriae
- Interstitium
Where is the ampulla of the fallopian tube?
Just after the fimbriae, but before the small neck, called the isthmus
What is the nucleus in the hypothalamus that produces ADH?
Supraoptic nucleus
What is the MOA of cilastatin, and what is it given with?
- Inhibits dehydropeptidase-1, and enzyme on the brush border of the proximal tubule.
- Imipenem
What is the ab that is detected in the nontreponemal test, and where in the body is this found?
- Anti-cardiolipin
- Inner mitochondrial membrane
What happens to the oxygen bindings curve for HbS during a sickle cell crisis?
Shifts right
Where is oxytocin stored?
Terminal swellings of the posterior hypothalamic neurons, known as Herring bodies
What causes the thrombocytopenia with Legionnaires disease?
Legionella inhibits ADAMS13, leading to a prothrombotic state
What is a palindromic DNA strand?
A strand where, when transcribed, leads to the same 5’ to 3’ sequence
What is the teratogenic effect of sulfamethoxazole?
Disrupts binding of indirect bilirubin to albumin, causing kernicterus in the developing fetus
What is the chromosome that MEN1 is on?
11
What chromosome is Rb found on?
13
What is the morphology of actinomyces? Aerobic? Treatment?
- Gram positive
- Anaerobe
- PCN
What is the gram stain, morphology, and aerobic/anaerobic characteristics of nocardia? Treatment?
- Gram positive aerobe
- Acid fast
- Sulfonamides
What lab is elevated with JIA?
ESR
What are the optic complications of JIA?
uveitis, leading to blindness
What are the s/sx of JIA? (3)
- Migratory polyarthritis
- Migratory rash
- Fever
What is Trousseau’s syndrome? What causes it?
Migratory thrombophlebitis 2/2 pancreatic cancer production of tissue factor
Which leukotrienes are most responsible for bronchoconstriction? (3)
LTC4 D4, and E4
What is the role of LTB4?
Chemoattractant for PMNs
What is the role of PGE2 on the lungs?
Causes bronchodilation
What is the role of prostacyclin?
Inhibits platelet aggregation
What is the treatment for schistosomiasis?
Praziquantel
