rad biology Flashcards

1
Q

law of bergonie and tribondeau

A

The radio sensitivity of a cell is directly proportional to reproductive rate, and is inversely proportional to its degree of differentiation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Radio sensitivity increases with

A

Increase rate of cell division
-Law degree of specialization
-Higher metabolic rate
-Increase oxygenation
Increased length of time they are actively proliferating. cell proliferation is the process by which a cell grows and divides to produce two daughter cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

cell cycle stages

A

G1: first growth phase
S: synthesis phase: S phase is the least radiosensitive phase of the cell, because the cell contains two copies of its DNA
G2: second growth phase
M: the cell divides into two cells in the process called mitosis. Mitosis is the most radiosensitive phase, because both mitosis is sensitive to destruction, and because the cell is well oxygenated during this phase.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Least radiosensitive

A

Synthesis phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

most radiosensitive

A

mitosis
-due to cells being well oxygenated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Lymphocytes

A

are the most radiosensitive blood cells
-whole body dose of 25 rads will depress flood count
-# 1!!!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

reproductive cells

A

very radiosensitive because there immature sperm cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

muscle

A

relatively insensitive, because of high specialization and lack of cell division 

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

nerve

A

low sensitivity, no division

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Most radiosensitive cells to least radiosensitive

A
  1. blood cells (bone marrow, lymphatic tissue)
    -lymphocytes, stem cells
    2.reproductive cells
    -immature sperm cells
    3.GI= small intestine- duodenum is most radiosensitive
    4.epithelial tissue
  2. muscle
  3. nerve
How well did you know this?
1
Not at all
2
3
4
5
Perfectly