Quiz 4 Study Guide: Renal Flashcards

1
Q

What are the symptoms of Urinary Obstruction?

A

Anuria
Polyuria
Bladder Distention
(Sometimes Asymptomatic)

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2
Q

Symptoms of Renal/Ureter stones

A

Renal Colic
Hematuria
Pyelonephritis
(Sometimes Asymptomatic)

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3
Q

What is Pyelonephritis?

A

Inflammation of Kidney tissue often caused by bacterial infection in or from the urinary tract.

  • Retrograde spread from Cystitis
  • Common with Urinary Obstruction, Stenosis
  • Diabetes
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4
Q

What are consequences of Pyelonephritis?

A

Flank Pain
Fever
Kidney Scarring
Chronic Renal Failure in 10-20%

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5
Q

What are properties of Renal Cell Carcinomas?

A

80-90% of renal malignancies
More common in males > 40 Yrs, and Smokers
Analgesic Users (NSAIDS)
Obesity

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6
Q

What are symptoms of Renal Cell Carcinomas?

A
Often Asymptomatic
Hematuria
Dull Flank Pain
Fever
Fatigue
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7
Q

Where do Renal Cell Carcinomas likely metastasize?

A

The Lungs or Bones

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8
Q

What is Wilms Tumor?

A

Most common childhood (Congenital) renal tumor

- Most common in first 3 years.

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9
Q

The two infections of the Bladder…

A

Bacterial Cystitis

Urothelial Carcinomas

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10
Q

What are contributing factors to Bacterial Cystitis?

A

Stones
Catheters
Short Female Urethras
Obstructions

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11
Q

What are the features of Urothelial Carcinomas?

A

Most often in males > 50 years old
Associated with Smoking (Carcinogens)
MOST COMMON urothelial malignancy

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12
Q

Three diseases of the Prostate

A

Prostatitis
Benign Prostatic Hyperplasia
Serum PSA and Prostatic Adenocarcinoma

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13
Q

What are the features or Prostatitis?

A

Often caused by bacteria (Cystitis)
Causes enlarged and tender prostate (Obstruction)
Most common in older men

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14
Q

What are the features of Benign Prostatic Hyperplasia?

A

Very common in older men (95% > 75 Years old)
Serious Sequelae less common
Cause not well known (maybe androgens or estrogens)
Urinary obstruction is common

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15
Q

What are the features of Prostatic Adenocarcinoma

A

The most common Malignancy in older men (other than skin cancers. (60% of men > 80 Years old)

Most often detected by rectal exams
Many are small and clinically irrelevant
*** can be deadly to some

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16
Q

What role does PSA (Prostate Specific Antigen) play?

A

Rapidly increasing PSA = High risk for cancer
>4-6 mg/ml is abnormal (usually with increased age)
The more PSA bound to alpha-1-antichymotrypsin, the greater the risk for cancer.

17
Q

What are the main causes of Chronic Renal Disease?

A

Diabetes, Hypertension, and chronic glomerulonephritis.

***26 million American adults have this. 500,000 on dialysis.

18
Q

The most common primary Glomerulonephritis is…

A

IgA nephropathy - triggered by a viral infection

19
Q

Chronic Renal Disease patients have…

A

Platelet dysfunctions (bleeding)
gingival hyperplasia
bone abnormalities (slow healing after surgery)
Premature bone loss (osteoporosis)
Infections complications (immunosuppression)

20
Q

What are common symptoms of Chronic Renal Disease

A

Heavy Proteinuria (Indicates renal cell death)
Hematuria
Inflammatory injury to kidneys
Glomeruli scarring and damaged function. (Sclerotic types)

21
Q

Treatments for Small Kidney Stones (

A

Drink lots of water
Dietary changes
OTC analgesics (ibuprofen and Naprosyn)
Tamulosin (Flomax) - Relaxes ureter muscle

22
Q

Treatments for Larger Kidney Stones

A

Lithotripsy (Shock-wave treatment)
Surgical removal
Opioid Analgesics for pain

23
Q

What are the 4 types of Kidney Stones?

A

Calcium/oxylate (80% of stones)
Struvite (10% of stones)
Uric Acid (gout)
Cysteine

24
Q

What is the only type of kidney stone that you treat by acidifying the urine?

A

Struvite stones

-Usually caused by urinary infections associated with magnesium ammonium phosphate crystals

25
Q

What are the 3 medications for Kidney stones?

A
  • Hydrochlorothiazide (Thiazide diuretic that reduces calcium in the urine.
  • Sodium Bicarbonate (Alkalinizes the urine)
  • Allopurinol (Reduces uric acid excretion)
26
Q

What causes Urinary Tract Infections?

A

Often E. Coli

Usually in Females

27
Q

What is the Treatment for UTI’s?

A

Trimethoprim-Sulfamethoxazole
Amoxicillin + Clavulanic Acid (Resistant bacteria)
Ciprofloxacin (expensive)

28
Q

What drugs are used for those receiving hemodialysis?

A

Atenolol and/or captopril for hypertension
Heparin (Prevents clotting during dialysis)
Furosemide
Prophylactic antibiotics (these pts. have high rate of infections)

29
Q

What is Furosemide?

A

Potent diuretic that reduces fled retention and the amount of fluid that needs to be removed by the dialysis.

30
Q

Dental Concerns of patients on Hemodialysis?

A

Higher incidence of Periodontal disease
More likely to have oral infections
Need for prophylactic antibiotics before treatment.